The Nedd4-like family of E3 ubiquitin ligases and cancer. - Wikidata - awgldk - TriplyDB

The Nedd4-like family of E3 ubiquitin ligases and cancer.

The Nedd4-like family of E3 ubiquitin ligases and cancer.

http://www.wikidata.org/entity/Q34668206

about

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1 WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer Smurf2 participates in human trophoblast cell invasion by inhibiting TGF-beta type I receptor SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Compartmentalization of aquaporins in the human intestine Targeting the ubiquitin pathway for cancer treatment NEDD4: a promising target for cancer therapy Nedd4 E3 ubiquitin ligase promotes cell proliferation and autophagy Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2)WW domain containing E3 ubiquitin protein ligase 1 (WWP1) negatively regulates TLR4-mediated TNF-α and IL-6 production by proteasomal degradation of TNF receptor associated factor 6 (TRAF6).Animal HECT ubiquitin ligases: evolution and functional implications.Transcription alterations of members of the ubiquitin-proteasome network in prostate carcinoma.Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells.SMURF1 amplification promotes invasiveness in pancreatic cancer.Two Nedd4-binding motifs underlie modulation of sodium channel Nav1.6 by p38 MAPK.The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation.Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets.Peptide and small molecule inhibitors of HECT-type ubiquitin ligases WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells.Identification of the NEDD4L gene as a prognostic marker by integrated microarray analysis of copy number and gene expression profiling in non-small cell lung cancer.gamma2-Adaptin, a ubiquitin-interacting adaptor, is a substrate to coupled ubiquitination by the ubiquitin ligase Nedd4 and functions in the endosomal pathway.Evolution of plant HECT ubiquitin ligases Nedd4-mediated AMPA receptor ubiquitination regulates receptor turnover and trafficking.Oxidative stress status accompanying diabetic bladder cystopathy results in the activation of protein degradation pathways Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1.A novel small-form NEDD4 regulates cell invasiveness and apoptosis to promote tumor metastasis.NEDD4 ubiquitin ligase is a putative oncogene in endometrial cancer that activates IGF-1R/PI3K/Akt signaling Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis.Conservation and evolutionary divergence in the activity of receptor-regulated smads Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma.Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth.Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes.Characterization of WWP1 protein expression in skeletal muscle of muscular dystrophy chickens.Copy number variation of E3 ubiquitin ligase genes in peripheral blood leukocyte and colorectal cancer.Regulating the stability of TGFbeta receptors and Smads.The HECTD3 E3 ubiquitin ligase facilitates cancer cell survival by promoting K63-linked polyubiquitination of caspase-8

P2860

Q24302375-80C54D6C-A13C-42BC-A94D-9E9B531F97A3 Q24309041-805C6881-92C8-43B4-AFE4-BE7EE3DB7FDA Q24316887-4F91E3E8-E0C5-4412-82B6-72FF766157E3 Q24567471-2154E38C-0E63-40B2-905C-7FD5520A48BD Q24647575-8A5C5D3D-9E00-426A-9B60-C85565DAD733 Q26866185-532D7CDA-D1E0-4C79-B08D-3EF566114536 Q27023899-2DE4A3A4-A565-4B5E-998B-7B4438E26A4E Q28119201-5D81269F-4A2D-442C-8228-92D41056A720 Q28297767-C1B29B31-0E13-4480-A672-F944D7ADAB2E Q28511737-0D12F15A-9CEB-4594-93D1-0CC94E789F2E Q28771737-1F064981-850D-4240-860F-B520DAE56038 Q30989535-919B66A6-AE88-4D4B-A1DF-A4BC5EFAA50E Q31121437-42CADB0B-A1DD-4E60-AC35-73004CD2D3E4 Q33533462-674236ED-5E15-427A-B243-34DE204F40F4 Q33753890-37E0414A-DC4D-49C7-9483-C29360013622 Q33893556-7C68D1E3-3E5E-481A-95AB-7B557ED51F20 Q34009701-83406036-B82F-40CF-A16D-BF007EC6CB62 Q34074334-673843B8-83EE-4DDE-BD65-A618E66834A4 Q34138871-2A1FB424-606D-4CD5-889E-2633596A6A83 Q34297948-2F4E1068-60F2-48BF-B190-48E0C2EDF435 Q34503492-4430F9C7-1B7B-4AC8-AB6D-B5F144A70D4A Q34601308-88A83228-30B6-4264-9935-C37181F76B7C Q34662167-1932B484-51B9-462C-BA97-DAD8196D8AD5 Q34787147-56F41755-44BF-4597-8263-F25186534D47 Q34821486-F9BF24E5-933F-43C4-841E-88127689D8DD Q34837810-131D2F54-BAB7-4529-8C45-278550319154 Q35033962-1D671B5D-935A-4EBD-820F-CA061C0F045E Q35168092-AAA93811-4164-44AE-9726-AE0131EAF3F6 Q35623029-E1C4B446-F54B-49F3-8BFC-14DB91161627 Q35832360-86939A59-626D-4B58-9430-7D92AFA5EB73 Q36101707-153318DF-3C90-4928-9E92-58A616411B88 Q36269300-D18929B1-B0FD-4B4B-8949-E0A3961C63A8 Q36406620-07FB4A83-6A6D-48CE-B1F4-12FDF7FCD89A Q36562214-B0EFFC66-5B10-4656-A6A0-829C55706032 Q36873676-1446AF80-924F-42FF-9124-10241E2E3A9F Q36887372-4E33FB34-F880-4AE3-99B1-683FA075CC1E Q36967780-17F4808A-89C0-484B-9B30-8B25C58BE775 Q37096504-B38C0902-597F-47F3-95EE-4A559828B090 Q37333694-32D9242E-228E-4BF1-A77A-74DFEC1CF808 Q37357126-E210A44E-5DEF-4E04-B061-05FCF87FA0E9

P2860

The Nedd4-like family of E3 ubiquitin ligases and cancer.

http://www.wikidata.org/entity/Q34668206

description

2007 nî lūn-bûn

@nan

2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@ast

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@en

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@nl

type

label

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@ast

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@en

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@nl

prefLabel

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@ast

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@en

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@nl

P1433

Q34668206-76D9FFA3-3CC9-43A5-A384-6E81D3AAD13B

P1476

Q34668206-3BEA7E7E-F780-42C9-80EB-FC6B3A5D82A8

P2093

Q34668206-57ACAE77-29F9-4413-925E-71A2297D5D64

Q34668206-B50C2202-1249-47BD-BA00-03DE26FE915E

P2860

Q34668206-20553C8B-0E8A-4DED-BA76-6738B052C885

Q34668206-30EAB177-8CB8-408E-BBD1-6F63261FCF87

Q34668206-8EB90523-9789-456D-AD00-F206408875AE

Q34668206-970FFD4B-703B-41EC-B08A-AFA843CF06C0

Q34668206-C501A92A-88B7-43A1-A937-17C1BF75EC7E

Q34668206-E3AFA845-EEDB-4DDB-8812-2E7CCDF46C1D

P2888

Q34668206-2E27E2A4-E38C-4D94-8E08-E3D11222E761

P304

Q34668206-6EFBFB7D-F73A-4790-8843-81A996755FF1

P31

Q34668206-1B862F85-3E85-4BBF-9F73-E30754D27EE5

P356

Q34668206-6FCD01E7-EEB4-4015-B800-1AE8EEF33225

P433

Q34668206-B4ABEE65-7A47-49FF-94E7-E48164A2ADA6

P478

Q34668206-59653827-7F42-43A2-904F-474EBDCC1189

P577

Q34668206-87A14859-5373-4D35-A6F0-C11FC406FC3F

P6179

Q34668206-BB4292B6-106F-4605-9392-B1490B7B4B25

P698

Q34668206-32BB5AB2-14A1-4B87-A23F-F0B2BE09F3C1

P356

S10555-007-9091-X

P1433

Cancer and Metastasis Reviews

P1476

The Nedd4-like family of E3 ubiquitin ligases and cancer.

@en

P2093

Ceshi Chen

http://www.w3.org/2001/XMLSchema#string

Lydia E Matesic

http://www.w3.org/2001/XMLSchema#string

P2860

Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors

The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases.

Itch/AIP4 associates with and promotes p63 protein degradation.

Destabilization of DeltaNp63alpha by Nedd4-mediated ubiquitination and Ubc9-mediated sumoylation, and its implications on dorsoventral patterning of the zebrafish embryo.

Multiple ubiquitin-dependent processing pathways regulate hedgehog/gli signaling: implications for cell development and tumorigenesis.

Degradation of p63 by Itch.

P2888

s10555-007-9091-x

P304

587-604

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S10555-007-9091-X

http://www.w3.org/2001/XMLSchema#string

P433

3-4

http://www.w3.org/2001/XMLSchema#string

P478

26

http://www.w3.org/2001/XMLSchema#string

P577

2007-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1012917799

http://www.w3.org/2001/XMLSchema#string

P698

17726579

http://www.w3.org/2001/XMLSchema#string