WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer
about
Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificityIntegrated genomic analyses identify frequent gene fusion events and VHL inactivation in gastrointestinal stromal tumorsEzrin ubiquitylation by the E3 ubiquitin ligase, WWP1, and consequent regulation of hepatocyte growth factor receptor activityWW domain containing E3 ubiquitin protein ligase 1 (WWP1) negatively regulates TLR4-mediated TNF-α and IL-6 production by proteasomal degradation of TNF receptor associated factor 6 (TRAF6).Overexpression of miR-584-5p inhibits proliferation and induces apoptosis by targeting WW domain-containing E3 ubiquitin protein ligase 1 in gastric cancer.The ubiquitin-proteasome system and assays to determine responses to inhibitors.E3 ubiquitin ligases in ErbB receptor quantity control.Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets.WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells.Structural insights into the functional versatility of WW domain-containing oxidoreductase tumor suppressor.The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts.Novel somatic mutations identified by whole-exome sequencing in muscle-invasive transitional cell carcinoma of the bladder.Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma.Endocytosis of receptor tyrosine kinasesMolecular origin of the binding of WWOX tumor suppressor to ErbB4 receptor tyrosine kinase.Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase.WWP1: a versatile ubiquitin E3 ligase in signaling and diseases.Crosstalk between kinases and Nedd4 family ubiquitin ligases.The Evaluation of WBP2NL-Related Genes Expression in Breast Cancer.Ubiquitination and the Regulation of Membrane Proteins.The WWP1 ubiquitin E3 ligase increases TRAIL resistance in breast cancer.FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator)The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation.Knockdown of WWP1 inhibits growth and invasion, but induces apoptosis of osteosarcoma cells.WWP1 as a potential tumor oncogene regulates PTEN-Akt signaling pathway in human gastric carcinoma.Estradiol promotes rapid degradation of HER3 in ER-positive breast cancer cell line MCF-7
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P248
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P2860
WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@ast
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@en
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@en-gb
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@nl
type
label
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@ast
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@en
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@en-gb
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@nl
prefLabel
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@ast
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@en
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@en-gb
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@nl
P2093
P2860
P3181
P356
P1433
P1476
WW domain containing E3 ubiqui ...... d degradation in breast cancer
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/ONC.2009.162
P407
P577
2009-06-29T00:00:00Z
P5875
P6179
1022785495