The awesome power of multiple model systems: interpreting the complex nature of spindle checkpoint signaling.
about
Identification of two novel components of the human NDC80 kinetochore complexImplication of ZW10 in membrane trafficking between the endoplasmic reticulum and GolgiConformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpointhNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cellsGenome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination.The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassemblyThe yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpointSpindle poisons and cell fate: a tale of two pathways.Plx1 is the 3F3/2 kinase responsible for targeting spindle checkpoint proteins to kinetochores.Recognizing chromosomes in trouble: association of the spindle checkpoint protein Bub3p with altered kinetochores and a unique defective centromere.Mal3, the fission yeast EB1 homologue, cooperates with Bub1 spindle checkpoint to prevent monopolar attachmentThe V260I mutation in fission yeast alpha-tubulin Atb2 affects microtubule dynamics and EB1-Mal3 localization and activates the Bub1 branch of the spindle checkpoint.The roles of fission yeast ase1 in mitotic cell division, meiotic nuclear oscillation, and cytokinesis checkpoint signalingThe A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint functionThe fission yeast Crb2/Chk1 pathway coordinates the DNA damage and spindle checkpoint in response to replication stress induced by topoisomerase I inhibitor.The spindle checkpoint, aneuploidy, and cancer.siRNA-mediated knockdown against NUF2 suppresses pancreatic cancer proliferation in vitro and in vivo.Loading of the 3F3/2 antigen onto kinetochores is dependent on the ordered assembly of the spindle checkpoint proteins.Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exitRNA interference, heterochromatin, and centromere function.Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p.Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint.DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.Kaposi's sarcoma-associated herpesvirus-encoded LANA can induce chromosomal instability through targeted degradation of the mitotic checkpoint kinase Bub1Inactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defects.Differential mode of regulation of the checkpoint kinases CHK1 and CHK2 by their regulatory domains.A delay like no other.
P2860
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P2860
The awesome power of multiple model systems: interpreting the complex nature of spindle checkpoint signaling.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The awesome power of multiple ...... spindle checkpoint signaling.
@ast
The awesome power of multiple ...... spindle checkpoint signaling.
@en
The awesome power of multiple ...... spindle checkpoint signaling.
@nl
type
label
The awesome power of multiple ...... spindle checkpoint signaling.
@ast
The awesome power of multiple ...... spindle checkpoint signaling.
@en
The awesome power of multiple ...... spindle checkpoint signaling.
@nl
prefLabel
The awesome power of multiple ...... spindle checkpoint signaling.
@ast
The awesome power of multiple ...... spindle checkpoint signaling.
@en
The awesome power of multiple ...... spindle checkpoint signaling.
@nl
P1476
The awesome power of multiple ...... spindle checkpoint signaling.
@en
P2093
David N Millband
Leigh Campbell
P304
P356
10.1016/S0962-8924(02)02276-6
P577
2002-05-01T00:00:00Z