Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
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Role of innate and drug-induced dysregulation of brain stress and arousal systems in addiction: Focus on corticotropin-releasing factor, nociceptin/orphanin FQ, and orexin/hypocretin.Orphanin FQ/nociceptin not only blocks but also reverses behavioral adaptive changes induced by repeated cocaine in miceThe Nociceptin Receptor as an Emerging Molecular Target for Cocaine AddictionThe endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine.The NOP (ORL1) receptor antagonist Compound B stimulates mesolimbic dopamine release and is rewarding in mice by a non-NOP-receptor-mediated mechanism.The role of mu opioid receptors in psychomotor stimulation and conditioned place preference induced by morphine-6-glucuronideRegarding "Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system".Nociceptin receptor activation does not alter acquisition, expression, extinction and reinstatement of conditioned cocaine preference in miceA neuropeptide-centric view of psychostimulant addictionNociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.Estradiol: a key biological substrate mediating the response to cocaine in female ratsThe role of NOP receptors in psychomotor stimulation and locomotor sensitization induced by cocaine and amphetamine in miceOrphanin FQ/nociceptin suppresses motor activity through an action along the mesoaccumbens axis in ratsThe biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence.Buprenorphine requires concomitant activation of NOP and MOP receptors to reduce cocaine consumption.Alterations in the level of OFQ/N-IR in rat brain regions by cocaine.Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence.ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine.Endogenous nociceptin (orphanin FQ) suppresses basal hedonic state and acute reward responses to methamphetamine and ethanol, but facilitates chronic responses.
P2860
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P2860
Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
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2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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name
Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
@ast
Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
@en
type
label
Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
@ast
Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
@en
prefLabel
Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
@ast
Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
@en
P2093
P2860
P1433
P1476
Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
@en
P2093
F Ivy Carroll
Imran Khaliq
Kabirullah Lutfy
Nigel T Maidment
P2860
P2888
P304
P356
10.1007/S00213-002-1192-1
P577
2002-08-30T00:00:00Z