Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology. - Wikidata - awgldk - TriplyDB

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

http://www.wikidata.org/entity/Q35155067

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Microglial Priming and Alzheimer's Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?Targeting innate immunity for neurodegenerative disorders of the central nervous system The dual roles of cytokines in Alzheimer's disease: update on interleukins, TNF-α, TGF-β and IFN-γ IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline.Balancing the immune response in the brain: IL-10 and its regulation Innate Immunity Fights Alzheimer's Disease Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease?Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.Neuroinflammation - using big data to inform clinical practice.Old Maids: Aging and Its Impact on Microglia Function.Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer's disease-like APPPS1 mice.Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment.Increase in the Inflammatory Marker GlycA over 13 Years in Young Adults Is Associated with Poorer Cognitive Function in Midlife.Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer's disease-like mice.Young microglia restore amyloid plaque clearance of aged microglia.A fresh perspective from immunologists and vaccine researchers: active vaccination strategies to prevent and reverse Alzheimer's disease.Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation.Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease.The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function.Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome Increased tauopathy drives microglia-mediated clearance of beta-amyloid.Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease.Laquinimod dampens hyperactive cytokine production in Huntington's disease patient myeloid cells.Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease.Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.Innate Immunity Stimulation via Toll-Like Receptor 9 Ameliorates Vascular Amyloid Pathology in Tg-SwDI Mice with Associated Cognitive Benefits.Protein misfolding in neurodegenerative diseases: implications and strategies.Type-I interferon pathway in neuroinflammation and neurodegeneration: focus on Alzheimer's disease.Essential Dietary Bioactive Lipids in Neuroinflammatory Diseases.Inflammatory Response in the CNS: Friend or Foe?Glial and Neuroimmune Mechanisms as Critical Modulators of Drug Use and Abuse.Multitasking Microglia and Alzheimer's Disease: Diversity, Tools and Therapeutic Targets.Cytokines and Cytokine Receptors Involved in the Pathogenesis of Alzheimer's Disease.Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice.

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Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

http://www.wikidata.org/entity/Q35155067

description

2015 nî lūn-bûn

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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2015年の論文

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2015年論文

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2015年論文

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2015年論文

@zh-hk

2015年論文

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2015年論文

@zh-tw

2015年论文

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name

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

@ast

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

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type

label

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

@ast

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

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prefLabel

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

@ast

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

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J.NEURON.2014.12.068

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Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.

@en

P2093

Brian P Leung

http://www.w3.org/2001/XMLSchema#string

Javier Rodriguez

http://www.w3.org/2001/XMLSchema#string

Kavon Rezai-Zadeh

http://www.w3.org/2001/XMLSchema#string

Kevin R Doty

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Marie-Victoire Guillot-Sestier

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Terrence Town

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P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry

The microglial "activation" continuum: from innate to adaptive responses

Innate immunity in Alzheimer's disease: a complex affair

Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

Expression and regulation of interleukin-10 and interleukin-10 receptor in rat astroglial and microglial cells

Open source clustering software

Interleukin-10-deficient mice develop chronic enterocolitis

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10.1016/J.NEURON.2014.12.068

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3

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25619654

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Alzheimer's disease

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4352138

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