Expression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancer.
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Chemotherapeutic sensitization of leptomycin B resistant lung cancer cells by pretreatment with doxorubicinStructural Basis of Targeting the Exportin CRM1 in CancerNuclear export of proteins and drug resistance in cancerSelective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemiaGenomic and molecular characterization of esophageal squamous cell carcinomaLongitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor.First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid TumorsPhase IB Study of Selinexor, a First-in-Class Inhibitor of Nuclear Export, in Patients With Advanced Refractory Bone or Soft Tissue Sarcoma.14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasisInhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins.Selinexor Overcomes Hypoxia-Induced Drug Resistance in Multiple Myeloma.KPT-330 has antitumour activity against non-small cell lung cancer.Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma.Atomic basis of CRM1-cargo recognition, release and inhibitionNovel small molecule XPO1/CRM1 inhibitors induce nuclear accumulation of TP53, phosphorylated MAPK and apoptosis in human melanoma cells.An intracellular targeted antibody detects EGFR as an independent prognostic factor in ovarian carcinomas.KPT-330 inhibitor of XPO1-mediated nuclear export has anti-proliferative activity in hepatocellular carcinoma.Targeting nucleocytoplasmic transport in cancer therapyInhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agentsSINE (selective inhibitor of nuclear export)--translational science in a new class of anti-cancer agentsNucleo-cytoplasmic transport as a therapeutic target of cancerPredicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemiaProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancerAntitumor effects of a novel chromosome region maintenance 1 (CRM1) inhibitor on non-small cell lung cancer cells in vitro and in mouse tumor xenografts.shRNA library screening identifies nucleocytoplasmic transport as a mediator of BCR-ABL1 kinase-independent resistance.LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins.XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A.Novel reversible selective inhibitor of CRM1 for targeted therapy in ovarian cancerThe Cellular Distribution of RanGAP1 Is Regulated by CRM1-Mediated Nuclear Export in Mammalian Cells.Deciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compoundsKPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models.Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein.Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.Selective Nuclear Export Inhibitor KPT-330 Enhances the Antitumor Activity of Gemcitabine in Human Pancreatic CancerHuman Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma.Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemiaNESdb: a database of NES-containing CRM1 cargoesTargeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells.Prognostic impact and targeting of CRM1 in acute myeloid leukemia.Chromosome region maintenance 1 expression and its association with clinical pathological features in primary carcinoma of the liver.
P2860
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P2860
Expression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancer.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Expression of the nuclear expo ...... actor in human ovarian cancer.
@ast
Expression of the nuclear expo ...... actor in human ovarian cancer.
@en
Expression of the nuclear expo ...... actor in human ovarian cancer.
@nl
type
label
Expression of the nuclear expo ...... actor in human ovarian cancer.
@ast
Expression of the nuclear expo ...... actor in human ovarian cancer.
@en
Expression of the nuclear expo ...... actor in human ovarian cancer.
@nl
prefLabel
Expression of the nuclear expo ...... actor in human ovarian cancer.
@ast
Expression of the nuclear expo ...... actor in human ovarian cancer.
@en
Expression of the nuclear expo ...... actor in human ovarian cancer.
@nl
P2093
P50
P356
P1433
P1476
Expression of the nuclear expo ...... actor in human ovarian cancer.
@en
P2093
Annika Röske
Carsten Denkert
P304
P356
10.1002/CNCR.23354
P407
P577
2008-04-01T00:00:00Z