about
Somatic hypermutation of the AID transgene in B and non-B cellsRegulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombinationActivation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNaseLack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining eventsMsh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombinationExamination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversificationComplex regulation of somatic hypermutation by cis-acting sequences in the endogenous IgH gene in hybridoma cellsGenotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families.Negative supercoiling creates single-stranded patches of DNA that are substrates for AID-mediated mutagenesis.Elevated incidence of polyp formation in APC(Min/⁺)Msh2⁻/⁻ mice is independent of nitric oxide-induced DNA mutationsAID to overcome the limitations of genomic information by introducing somatic DNA alterations.Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination.Mismatch repair system in endometriotic tissue and eutopic endometrium of unaffected womenMechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects.Single-stranded DNA structure and positional context of the target cytidine determine the enzymatic efficiency of AID.DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination.DNA repair in antibody somatic hypermutation.RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cellsDNA replication to aid somatic hypermutationAccumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutationNF-IL6 (C/EBPbeta) induces HIV-1 replication by inhibiting cytidine deaminase APOBEC3G.DNA repair mechanisms and Toxoplasma gondii infection.Differential regulation of histone acetylation and generation of mutations in switch regions is associated with Ig class switching.Evolution of new nonantibody proteins via iterative somatic hypermutation.YY1 controls immunoglobulin class switch recombination and nuclear activation-induced deaminase levels.Novel antibody switching defects in human patients.NHEJ-deficient DT40 cells have increased levels of immunoglobulin gene conversion: evidence for a double strand break intermediate.The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination.AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner.Diversity Generator Mechanisms Are Essential Components of Biological Systems: The Two Queen Hypothesis.
P2860
Q24535846-D9EE96D5-B694-45FC-9840-234D1215E161Q24633098-B7D36698-A5F7-4DA8-8C0D-E679B2A347C1Q24683335-CC7B7C7C-2453-4C9D-8AF3-322993A3C971Q24813835-F4984743-EB74-46F2-A7A1-A42F7F0E990EQ28586272-ED1AF605-0C90-4D0E-8693-CCC942B8D977Q28589828-6BBB9FDD-AEA5-49FA-8C05-F490EB7F038BQ33920280-AEE2A062-3A5B-421A-A8A1-3736405AC259Q33939068-14A5FB80-7397-438E-87E3-AA679DEBD78FQ34162337-E2C9ECB7-54F8-44AD-A011-59D8A296529DQ34761307-7457A68A-52EA-4080-98D6-C6CC88FDB88DQ35068183-078E175A-3444-4A96-9C0F-C794642A48C3Q35108519-408E653D-8758-49A8-8C26-9FD16B354853Q35406659-3837776E-CBD7-422D-B78E-60FCB8C749ACQ36157946-92111D74-9FCC-483E-903D-2097F06F9F12Q36315914-E50EC038-F542-4A45-94A1-9EBF03E5EA06Q36399002-8E5FCBC1-0480-4695-9663-1DC829353AD9Q36493831-AFED4E4C-937E-4ED3-ADB1-3C8B4BD54E59Q36689901-41BAF8F9-1C6E-4D83-9D6B-7EB2CBDC2F9DQ36751819-C9A70673-8004-4876-BADF-251685F138CCQ36835721-1B59BD85-F02C-4DAA-A38D-D98AA1C52AC7Q36937148-6A00A147-CC3B-4019-85CD-7198727C8944Q37471650-A19B1F0D-36DB-4723-A99B-49346954FA46Q37593556-F6D2D8B5-2E85-4DCC-A6BA-675DE1467B28Q37627375-EC808384-DCD9-461C-8703-AE32A06B8DD3Q39404034-F60DB72E-265C-425D-973F-C2C43916F613Q39778185-B6F7F5A0-D733-4013-B3BD-076486F2F96DQ40105785-B5A2BA5A-3C63-4CB1-AA9B-1626437E92DAQ41493193-8A2E4AA7-A4DD-4DCC-BD9A-2E38F69B9413Q42101206-CC61D7F8-45A7-4AE9-9526-6DA3C53436F1Q50322322-E2C64C8F-59F9-42C4-8BC2-8C2C60F039CA
P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
AID and mismatch repair in antibody diversification.
@ast
AID and mismatch repair in antibody diversification.
@en
AID and mismatch repair in antibody diversification.
@nl
type
label
AID and mismatch repair in antibody diversification.
@ast
AID and mismatch repair in antibody diversification.
@en
AID and mismatch repair in antibody diversification.
@nl
prefLabel
AID and mismatch repair in antibody diversification.
@ast
AID and mismatch repair in antibody diversification.
@en
AID and mismatch repair in antibody diversification.
@nl
P2860
P356
P1476
AID and mismatch repair in antibody diversification.
@en
P2093
Alberto Martin
Matthew D Scharff
P2860
P2888
P304
P356
10.1038/NRI858
P577
2002-08-01T00:00:00Z
P5875
P6179
1041294141