Multiple functional elements comprise a Mammalian chromosomal replicator.
about
The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cellsDNA binding and helicase actions of mouse MCM4/6/7 helicase.PATTERNFINDER: combined analysis of DNA regulatory sequences and double-helix stabilityInitiation of DNA replication at the human beta-globin 3' enhancer.Peaks cloaked in the mist: the landscape of mammalian replication originsStructure and function of the c-myc DNA-unwinding element-binding protein DUE-BA winding road to origin discoveryA revisionist replicon model for higher eukaryotic genomes.Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cellsAn episomal mammalian replicon: sequence-independent binding of the origin recognition complex.The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation.Preferential localization of human origins of DNA replication at the 5'-ends of expressed genes and at evolutionarily conserved DNA sequences.In search of the holy replicatorThe replicon revisited: an old model learns new tricks in metazoan chromosomesEvaluating genome-scale approaches to eukaryotic DNA replication.Chromatin structure and replication origins: determinants of chromosome replication and nuclear organizationReplication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract.Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zoneDissection of the beta-globin replication-initiation region reveals specific requirements for replicator elements during gene amplificationDifferential binding of replication proteins across the human c-myc replicator.The hunt for origins of DNA replication in multicellular eukaryotesAn origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) geneDiscrete functional elements required for initiation activity of the Chinese hamster dihydrofolate reductase origin beta at ectopic chromosomal sites.Genomic specification and epigenetic regulation of eukaryotic DNA replication originsAltered replication in human cells promotes DMPK (CTG)(n) · (CAG)(n) repeat instabilityOligodeoxynucleotide binding to (CTG) · (CAG) microsatellite repeats inhibits replication fork stalling, hairpin formation, and genome instability.Modular structure of the human lamin B2 replicator.Activation of a human chromosomal replication origin by protein tethering.Replication origins: determinants or consequences of nuclear organization?FANCJ is essential to maintain microsatellite structure genome-wide during replication stress.The human beta-globin replication initiation region consists of two modular independent replicatorsNuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome.G4 motifs affect origin positioning and efficiency in two vertebrate replicators.Defined sequence modules and an architectural element cooperate to promote initiation at an ectopic mammalian chromosomal replication origin.The c-myc DNA-unwinding element-binding protein modulates the assembly of DNA replication complexes in vitro.Transcription factor binding and induced transcription alter chromosomal c-myc replicator activity.Order from clutter: selective interactions at mammalian replication origins.Replication stalling and DNA microsatellite instability.Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability.Replication-dependent instability at (CTG) x (CAG) repeat hairpins in human cells.
P2860
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P2860
Multiple functional elements comprise a Mammalian chromosomal replicator.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Multiple functional elements comprise a Mammalian chromosomal replicator.
@ast
Multiple functional elements comprise a Mammalian chromosomal replicator.
@en
Multiple functional elements comprise a Mammalian chromosomal replicator.
@nl
type
label
Multiple functional elements comprise a Mammalian chromosomal replicator.
@ast
Multiple functional elements comprise a Mammalian chromosomal replicator.
@en
Multiple functional elements comprise a Mammalian chromosomal replicator.
@nl
prefLabel
Multiple functional elements comprise a Mammalian chromosomal replicator.
@ast
Multiple functional elements comprise a Mammalian chromosomal replicator.
@en
Multiple functional elements comprise a Mammalian chromosomal replicator.
@nl
P2093
P2860
P1476
Multiple functional elements comprise a Mammalian chromosomal replicator.
@en
P2093
Michael Leffak
Michelle Malott
P2860
P304
P356
10.1128/MCB.23.5.1832-1842.2003
P407
P577
2003-03-01T00:00:00Z