The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control. - Wikidata - awgldk - TriplyDB

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

http://www.wikidata.org/entity/Q34911467

about

Interactions of the human MCM-BP protein with MCM complex components and Dbf4 Transducer of ERBB2.1 (TOB1) as a Tumor Suppressor: A Mechanistic Perspective Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae.Drf1-dependent kinase interacts with Claspin through a conserved protein motif.Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damage Regulation and roles of Cdc7 kinase under replication stress.Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells.SIRT1 deacetylates TopBP1 and modulates intra-S-phase checkpoint and DNA replication origin firing The fork and the kinase: a DNA replication tale from a CHK1 perspective.Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpoint Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest.Cell-free Xenopus egg extracts for studying DNA damage response pathways.Molecular mechanisms of DNA replication checkpoint activation Roles of CDK and DDK in Genome Duplication and Maintenance: Meiotic Singularities.ATR: a master conductor of cellular responses to DNA replication stress.Xenopus white papers and resources: folding functional genomics and genetics into the frog.Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob.A synthetic human kinase can control cell cycle progression in budding yeast.Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits.Replication checkpoint: tuning and coordination of replication forks in s phase.Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1.Research highlights on a notable retrovirus and a popular guardian gene.Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer.Cyclin E goes nuts: a cell cycle regulator affects male fertility.

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The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

http://www.wikidata.org/entity/Q34911467

description

2008 nî lūn-bûn

@nan

2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

@ast

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

@en

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

@nl

type

label

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

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The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

@en

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

@nl

prefLabel

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

@ast

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

@en

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.

@nl

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The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control

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Eric Lau

http://www.w3.org/2001/XMLSchema#string

Toshiya Tsuji

http://www.w3.org/2001/XMLSchema#string

Wei Jiang

http://www.w3.org/2001/XMLSchema#string

P2860

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells

Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

Cdc7-Dbf4 and the human S checkpoint response to UVC

Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin

DNA replication in eukaryotic cells

An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication

Checkpoint and coordinated cellular responses to DNA damage

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