Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
about
P1343
Ovarian Cancer: The Fallopian Tube as the Site of Origin and Opportunities for PreventionRethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancerClaudins overexpression in ovarian cancer: potential targets for Clostridium Perfringens Enterotoxin (CPE) based diagnosis and therapyEGFR/HER-targeted therapeutics in ovarian cancerThe molecular fingerprint of high grade serous ovarian cancer reflects its fallopian tube originSociety of Gynecologic Oncology recommendations for the prevention of ovarian cancerCurrent status and evolution of preclinical drug development models of epithelial ovarian cancerMutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition.Identification of quiescent, stem-like cells in the distal female reproductive tractRegulation of the Epithelial-Mesenchymal Transition by Claudin-3 and Claudin-4Molecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma.Mesenchymal gene program-expressing ovarian cancer spheroids exhibit enhanced mesothelial clearanceStem-like epithelial cells are concentrated in the distal end of the fallopian tube: a site for injury and serous cancer initiation.Novel population of small tumour-initiating stem cells in the ovaries of women with borderline ovarian cancerMolecular profiling and clinical outcome of high-grade serous ovarian cancer presenting with low- versus high-volume ascites.Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors.Multi-peptide nLC-PC-IDMS-SRM-based assay for the quantification of biomarkers in the chicken ovarian cancer modelComing into focus: the nonovarian origins of ovarian cancer.Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.New views on the pathogenesis of high-grade pelvic serous carcinoma with suggestions for advancing future researchEffect of tubal sterilization technique on risk of serous epithelial ovarian and primary peritoneal carcinomaIn vitro three-dimensional modeling of fallopian tube secretory epithelial cells.Notch3 overexpression promotes anoikis resistance in epithelial ovarian cancer via upregulation of COL4A2.Gene expression signature of normal cell-of-origin predicts ovarian tumor outcomes.Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence.Mutation or loss of p53 differentially modifies TGFβ action in ovarian cancerProgesterone action in breast, uterine, and ovarian cancers.Three-dimensional modeling of the human fallopian tube fimbriaeThe Tyrosine Kinase Adaptor Protein FRS2 Is Oncogenic and Amplified in High-Grade Serous Ovarian CancerStathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas.The new face of ovarian cancer modeling: better prospects for detection and treatment.Three-dimensional modeling of ovarian cancer.Stromal Expression of Fibroblast Activation Protein Alpha (FAP) Predicts Platinum Resistance and Shorter Recurrence in patients with Epithelial Ovarian Cancer.Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cellsCell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancerMutant p53 expression in fallopian tube epithelium drives cell migrationSpontaneous Transformation of Murine Oviductal Epithelial Cells: A Model System to Investigate the Onset of Fallopian-Derived Tumors.Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube-derived high-grade serous ovarian cancers.An apoptosis-enhancing drug overcomes platinum resistance in a tumour-initiating subpopulation of ovarian cancer.
P2860
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P2860
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
description
2011 nî lūn-bûn
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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2011 թվականի ապրիլին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
@zh-cn
2011年学术文章
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2011年学术文章
@zh-my
2011年学术文章
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2011年學術文章
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name
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@ast
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@en
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@nl
type
label
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@ast
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@en
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@nl
prefLabel
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@ast
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@en
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@nl
P2860
P356
P1476
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
@en
P2093
Alison M Karst
P2860
P304
P356
10.1073/PNAS.1017300108
P407
P4510
P577
2011-04-18T00:00:00Z