Effect of glycans and the glycophosphatidylinositol anchor on strain dependent conformations of scrapie prion protein: improved purifications and infrared spectra.
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The Structural Architecture of an Infectious Mammalian Prion Using Electron CryomicroscopyEfficient uptake and dissemination of scrapie prion protein by astrocytes and fibroblasts from adult hamster brainPK-sensitive PrP is infectious and shares basic structural features with PK-resistant PrPPrion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuICDefining the conformational features of anchorless, poorly neuroinvasive prionsParallel in-register intermolecular β-sheet architectures for prion-seeded prion protein (PrP) amyloids.Post-translational modifications in PrP expand the conformational diversity of prions in vivoMammalian prions: tolerance to sequence changes-how far?Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells.The structure of the infectious prion protein: experimental data and molecular models.Glycosylphosphatidylinositol anchoring directs the assembly of Sup35NM protein into non-fibrillar, membrane-bound aggregatesHigh-resolution structure of infectious prion protein: the final frontierPropagation of RML prions in mice expressing PrP devoid of GPI anchor leads to formation of a novel, stable prion strainProteomics analysis of amyloid and nonamyloid prion disease phenotypes reveals both common and divergent mechanisms of neuropathogenesisStructural organization of mammalian prions as probed by limited proteolysis.Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid.Prions on the move.Dual conformation of H2H3 domain of prion protein in mammalian cells.A novel and rapid method for obtaining high titre intact prion strains from mammalian brain.Increased infectivity of anchorless mouse scrapie prions in transgenic mice overexpressing human prion proteinA Structural and Functional Comparison Between Infectious and Non-Infectious Autocatalytic Recombinant PrP Conformers.Reaction of complement factors varies with prion strains in vitro and in vivo.Integrity of helix 2-helix 3 domain of the PrP protein is not mandatory for prion replication.Isolation of novel synthetic prion strains by amplification in transgenic mice coexpressing wild-type and anchorless prion proteins.Detection of Atypical H-Type Bovine Spongiform Encephalopathy and Discrimination of Bovine Prion Strains by Real-Time Quaking-Induced Conversion.Prions and the potential transmissibility of protein misfolding diseasesPrPSc-Specific Antibody Reveals C-Terminal Conformational Differences between Prion Strains.Identification and removal of proteins that co-purify with infectious prion protein improves the analysis of its secondary structure.Generating Bona Fide Mammalian Prions with Internal DeletionsConformational stability of mammalian prion protein amyloid fibrils is dictated by a packing polymorphism within the core region.PrP Knockout Cells Expressing Transmembrane PrP Resist Prion InfectionPrion disease: a tale of folds and strains.The structure of human prions: from biology to structural models-considerations and pitfalls.Proteomics applications in prion biology and structure.Caprine PrP variants harboring Asp-146, His-154 and Gln-211 alleles display reduced convertibility upon interaction with pathogenic murine prion protein in scrapie infected cells.Structural Biology of PrP Prions.Reversible unfolding of infectious prion assemblies reveals the existence of an oligomeric elementary brick.Immunodetection of PrPSc Using Western Immunoblotting Techniques.Generation of a new infectious recombinant prion: a model to understand Gerstmann-Sträussler-Scheinker syndrome.A stretch of residues within the protease-resistant core is not necessary for prion structure and infectivity.
P2860
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P2860
Effect of glycans and the glycophosphatidylinositol anchor on strain dependent conformations of scrapie prion protein: improved purifications and infrared spectra.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Effect of glycans and the glyc ...... ications and infrared spectra.
@ast
Effect of glycans and the glyc ...... ications and infrared spectra.
@en
type
label
Effect of glycans and the glyc ...... ications and infrared spectra.
@ast
Effect of glycans and the glyc ...... ications and infrared spectra.
@en
prefLabel
Effect of glycans and the glyc ...... ications and infrared spectra.
@ast
Effect of glycans and the glyc ...... ications and infrared spectra.
@en
P2093
P2860
P356
P1433
P1476
Effect of glycans and the glyc ...... ications and infrared spectra.
@en
P2093
Andrew G Hughson
David W Dorward
Gerald S Baron
Gregory J Raymond
Kelly A Barton
Lynne D Raymond
P2860
P304
P356
10.1021/BI2003907
P407
P577
2011-05-03T00:00:00Z