p38MAPK inhibition prevents disease in pemphigus vulgaris mice. - Wikidata - awgldk - TriplyDB

p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

http://www.wikidata.org/entity/Q35036492

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The desmosome Desmosomes in acquired disease Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism Inhibition of Rho A activity causes pemphigus skin blistering.Pemphigus vulgaris IgG cause loss of desmoglein-mediated adhesion and keratinocyte dissociation independent of epidermal growth factor receptor Peptides Targeting the Desmoglein 3 Adhesive Interface Prevent Autoantibody-induced Acantholysis in Pemphigus.Desmocollin 3-mediated binding is crucial for keratinocyte cohesion and is impaired in pemphigus.Antimitochondrial autoantibodies in pemphigus vulgaris: a missing link in disease pathophysiology Increased miR-424-5p expression in peripheral blood mononuclear cells from patients with pemphigus p38MAPK signaling and desmoglein-3 internalization are linked events in pemphigus acantholysis.Mechanisms of Autoantibody-Induced Pathology.Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies.Protein kinase D as a potential new target for cancer therapy.Tyrosine kinases in inflammatory dermatologic disease.p38 MAPK activation is downstream of the loss of intercellular adhesion in pemphigus vulgaris.Signaling dependent and independent mechanisms in pemphigus vulgaris blister formation Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion.Desmoglein as a target in skin disease and beyond.The C5a receptor on mast cells is critical for the autoimmune skin-blistering disease bullous pemphigoid.Structure, function, and regulation of desmosomes.The extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?Update on fogo selvagem, an endemic form of pemphigus foliaceus Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blistering Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide Pemphigus antibody induced phosphorylation of keratinocyte proteins.The desmosome and pemphigus.A pathophysiologic role for epidermal growth factor receptor in pemphigus acantholysis p38 MAPK signaling in oral-related diseases.Autoantibodies in the autoimmune disease pemphigus foliaceus induce blistering via p38 mitogen-activated protein kinase-dependent signaling in the skin Seeking approval: present and future therapies for pemphigus vulgaris Advances in pemphigus and its endemic pemphigus foliaceus (Fogo Selvagem) phenotype: a paradigm of human autoimmunity.Involvement of the apoptotic mechanism in pemphigus foliaceus autoimmune injury of the skin.Disruption of desmosome assembly by monovalent human pemphigus vulgaris monoclonal antibodies.Setting the target for pemphigus vulgaris therapy.Apoptotic pathways in pemphigus.Pemphigus autoimmunity: hypotheses and realities.Urban legends: pemphigus vulgaris.Desmoglein 3, its pathogenecity and a possibility for therapeutic target in pemphigus vulgaris.

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p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

http://www.wikidata.org/entity/Q35036492

description

2006 nî lūn-bûn

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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年學術文章

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name

p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

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p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

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type

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p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

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p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

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prefLabel

p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

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p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

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Proceedings of the National Academy of Sciences of the United States of America

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p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

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David S Rubenstein

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Luis A Diaz

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Paula Berkowitz

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Peiqi Hu

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Simon Warren

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Zhi Liu

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P2860

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27

MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha

Are desmosomes more than tethers for intermediate filaments?

Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

Regulation of cadherin-mediated adhesion in morphogenesis

The cadherin-catenin adhesion system in signaling and cancer.

Monovalent Fab' immunoglobulin fragments from endemic pemphigus foliaceus autoantibodies reproduce the human disease in neonatal Balb/c mice

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.

Identification of pemphigus vulgaris antigen extracted from normal human epidermis and comparison with pemphigus foliaceus antigen

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