A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein
about
Design of versatile biochemical switches that respond to amplitude, duration, and spatial cuesStructure of the N-terminal Gyrase B fragment in complex with ADP⋅Pi reveals rigid-body motion induced by ATP hydrolysisStructural and Enzymatic Insights into the ATP Binding and Autophosphorylation Mechanism of a Sensor Histidine KinaseCatalytic mechanism of a mammalian Rab{middle dot}RabGAP complex in atomic detailPhosphate vibrations probe local electric fields and hydration in biomoleculesOverview of simulation studies on the enzymatic activity and conformational dynamics of the GTPase Ras.Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations.The GAP arginine finger movement into the catalytic site of Ras increases the activation entropyCofactor dependent conformational switching of GTPases.Mechanism of the chemical step for the guanosine triphosphate (GTP) hydrolysis catalyzed by elongation factor TuThe dynamics of the catalytic site in small GTPases, variations on a common motif.Invited review: Small GTPases and their GAPs.Unravelling the mechanism of dual-specificity GAPs.Integration of Fourier Transform Infrared Spectroscopy, Fluorescence Spectroscopy, Steady-state Kinetics and Molecular Dynamics Simulations of Gαi1 Distinguishes between the GTP Hydrolysis and GDP Release Mechanism.SEIRA spectroscopy on a membrane receptor monolayer using lipoprotein particles as carriers.The role of magnesium for geometry and charge in GTP hydrolysis, revealed by quantum mechanics/molecular mechanics simulations.Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal thermophilic ATP-driven heavy metal transporter.Label-free screening of drug-protein interactions by time-resolved Fourier transform infrared spectroscopic assays exemplified by Ras interactions.Energetics of activation of GTP hydrolysis on the ribosome.Fluoride complexes of oncogenic Ras mutants to study the Ras-RasGap interaction.Role of the arginine finger in Ras.RasGAP revealed by QM/MM calculations.Microhydrated dihydrogen phosphate clusters probed by gas phase vibrational spectroscopy and first principles calculations.Mechanistic Insights into the Differential Catalysis by RheB and Its Mutants: Y35A and Y35A-D65A.
P2860
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P2860
A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A phosphoryl transfer intermed ...... its GTPase-activating protein
@ast
A phosphoryl transfer intermed ...... its GTPase-activating protein
@en
type
label
A phosphoryl transfer intermed ...... its GTPase-activating protein
@ast
A phosphoryl transfer intermed ...... its GTPase-activating protein
@en
prefLabel
A phosphoryl transfer intermed ...... its GTPase-activating protein
@ast
A phosphoryl transfer intermed ...... its GTPase-activating protein
@en
P2860
P50
P356
P1476
A phosphoryl transfer intermed ...... its GTPase-activating protein
@en
P2093
Marco Blessenohl
P2860
P304
13911-13916
P356
10.1073/PNAS.0604128103
P407
P577
2006-09-12T00:00:00Z