Establishment, maintenance and in vitro and in vivo applications of primary human glioblastoma multiforme (GBM) xenograft models for translational biology studies and drug discovery.
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Gene therapy for brain tumors: basic developments and clinical implementationPenfluridol suppresses glioblastoma tumor growth by Akt-mediated inhibition of GLI1.Inhibition of BET bromodomain targets genetically diverse glioblastomaRedox-responsive magnetic nanoparticle for targeted convection-enhanced delivery of O6-benzylguanine to brain tumorsA genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas.Targeting Src family kinases inhibits bevacizumab-induced glioma cell invasionBET bromodomain proteins are required for glioblastoma cell proliferation.The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in GlioblastomaAntiproliferative and apoptosis-inducing activity of schisandrin B against human glioma cells.ROCK Inhibition Facilitates In Vitro Expansion of Glioblastoma Stem-Like Cells.Critical functions of RhoB in support of glioblastoma tumorigenesisEfficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System.Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development.Effective radiovirotherapy for malignant gliomas by using oncolytic measles virus strains encoding the sodium iodide symporter (MV-NIS).p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells.Src family kinases differentially influence glioma growth and motilityIdentification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cellsIdentification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells.Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.Genetically engineered rat gliomas: PDGF-driven tumor initiation and progression in tv-a transgenic rats recreate key features of human brain cancer.Molecular characterization of EGFR and EGFRvIII signaling networks in human glioblastoma tumor xenografts.Factors Influencing the Central Nervous System Distribution of a Novel Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor GSK2126458: Implications for Overcoming Resistance with Combination Therapy for Melanoma Brain Metastases.Patient-Derived Xenografts as a Model System for Radiation ResearchRetinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins.In Vivo c-Met Pathway Inhibition Depletes Human Glioma Xenografts of Tumor-Propagating Stem-Like CellsInsR/IGF1R Pathway Mediates Resistance to EGFR Inhibitors in Glioblastoma.Method for lipidomic analysis: p53 expression modulation of sulfatide, ganglioside, and phospholipid composition of U87 MG glioblastoma cellsDelineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of GlioblastomaColony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization.Carbenoxolone enhances TRAIL-induced apoptosis through the upregulation of death receptor 5 and inhibition of gap junction intercellular communication in human glioma.Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma.Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade gliomaInhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo.Network Modeling Identifies Patient-specific Pathways in Glioblastoma.Brain tumor stem cell multipotency correlates with nanog expression and extent of passaging in human glioblastoma xenografts.Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis in vitro and in vivoSDF-1 Blockade Enhances Anti-VEGF Therapy of Glioblastoma and Can Be Monitored by MRI.p53 isoform profiling in glioblastoma and injured brain.Cyclophilin B supports Myc and mutant p53-dependent survival of glioblastoma multiforme cells.Optimized creation of glioblastoma patient derived xenografts for use in preclinical studies.
P2860
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P2860
Establishment, maintenance and in vitro and in vivo applications of primary human glioblastoma multiforme (GBM) xenograft models for translational biology studies and drug discovery.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Establishment, maintenance and ...... gy studies and drug discovery.
@ast
Establishment, maintenance and ...... gy studies and drug discovery.
@en
type
label
Establishment, maintenance and ...... gy studies and drug discovery.
@ast
Establishment, maintenance and ...... gy studies and drug discovery.
@en
prefLabel
Establishment, maintenance and ...... gy studies and drug discovery.
@ast
Establishment, maintenance and ...... gy studies and drug discovery.
@en
P2093
P2860
P1476
Establishment, maintenance and ...... gy studies and drug discovery.
@en
P2093
Brett L Carlson
Jann N Sarkaria
Jenny L Pokorny
Mark A Schroeder
P2860
P304
Unit 14.16
P356
10.1002/0471141755.PH1416S52
P478
Chapter 14
P577
2011-03-01T00:00:00Z