A positive role for c-Abl in Atm and Atr activation in DNA damage response. - Wikidata - awgldk - TriplyDB

A positive role for c-Abl in Atm and Atr activation in DNA damage response.

A positive role for c-Abl in Atm and Atr activation in DNA damage response.

http://www.wikidata.org/entity/Q35092564

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Rho GTPases: Novel Players in the Regulation of the DNA Damage Response?Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone Identification of 5-Iodotubercidin as a genotoxic drug with anti-cancer potential c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression c-Abl mediates angiotensin II-induced apoptosis in podocytes Biological Chemistry and Functionality of Protein Sulfenic Acids and Related Thiol Modifications A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.Global Regulation of Differential Gene Expression by c-Abl/Arg Oncogenic Kinases.c-Abl regulates gastrointestinal muscularis propria homeostasis via ERKs Bioinformatics study of cancer-related mutations within p53 phosphorylation site motifs AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts.DNA mismatch repair gene MLH1 induces apoptosis in prostate cancer cells.Ribosomal S6 Kinase 2 (RSK2) maintains genomic stability by activating the Atm/p53-dependent DNA damage pathway Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death.Regulation of p73 activity by post-translational modifications.A potential role for protein palmitoylation and zDHHC16 in DNA damage response.Tissue-specific expression of p73 C-terminal isoforms in mice.P73 and age-related diseases: is there any link with Parkinson Disease?The dynamic behavior of Ect2 in response to DNA damage.A role for c-Abl in cell senescence and spontaneous immortalization.Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.Defying DNA double-strand break-induced death during prophase I meiosis by temporal TAp63α phosphorylation regulation in developing mouse oocytes.ATM protein kinase: the linchpin of cellular defenses to stress.The TP73 complex network: ready for clinical translation in cancer?An unconventional role of BMP-Smad1 signaling in DNA damage response: a mechanism for tumor suppression.Role of the nucleus in apoptosis: signaling and execution.Nuclear Gene 33/Mig6 Regulates the DNA Damage Response through an ATM-dependent Mechanism.The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage.Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation.Trace levels of mitomycin C disrupt genomic integrity and lead to DNA damage response defect in long-term-cultured human embryonic stem cells.Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint.KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling Identification of NCF2/p67phox as a novel p53 target gene ABL regulation by AXL promotes cisplatin resistance in esophageal cancer.Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis.The emerging role of alternative splicing in senescence and aging.Improvement of gemcitabine sensitivity of p53-mutated pancreatic cancer MiaPaCa-2 cells by RUNX2 depletion-mediated augmentation of TAp73-dependent cell death.Philadelphia chromosome-negative acute myeloid leukemia with 11q23/MLL translocation in a patient with chronic myelogenous leukemia Metabolic profiling of human CD4+ cells following treatment with methotrexate and anti-TNF-α infliximab.c-Abl tyrosine kinase in the DNA damage response: cell death and more

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A positive role for c-Abl in Atm and Atr activation in DNA damage response.

http://www.wikidata.org/entity/Q35092564

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

A positive role for c-Abl in Atm and Atr activation in DNA damage response.

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A positive role for c-Abl in Atm and Atr activation in DNA damage response.

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type

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A positive role for c-Abl in Atm and Atr activation in DNA damage response.

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A positive role for c-Abl in Atm and Atr activation in DNA damage response.

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A positive role for c-Abl in Atm and Atr activation in DNA damage response.

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A positive role for c-Abl in Atm and Atr activation in DNA damage response.

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Cell Death & Differentiation

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A positive role for c-Abl in Atm and Atr activation in DNA damage response

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P2860

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

Regulation of Rad51 function by c-Abl in response to DNA damage

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity

Transcriptional consequences of topoisomerase inhibition

c-Abl: activation and nuclear targets

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

Substrate specificities and identification of putative substrates of ATM kinase family members

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

Interaction between ATM protein and c-Abl in response to DNA damage

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10.1038/CDD.2010.106

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