Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.
about
Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosisActivation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxisSHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.Shc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cellsHuman piebald trait resulting from a dominant negative mutant allele of the c-kit membrane receptor geneDifferential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotypeEnhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, LnkOne-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probesFunctional deregulation of KIT: link to mast cell proliferative diseases and other neoplasmsReceptor tyrosine kinase signaling: regulating neural crest development one phosphate at a timeKit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferationMutation D816V alters the internal structure and dynamics of c-KIT receptor cytoplasmic region: implications for dimerization and activation mechanismsIsolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epitheliumImpairment of spatial learning and hippocampal synaptic potentiation in c-kit mutant ratsActivation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthmaMutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblastsTyrosine 569 in the c-Fms juxtamembrane domain is essential for kinase activity and macrophage colony-stimulating factor-dependent internalizationc-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas.Random mutagenesis of CSF-1 receptor (FMS) reveals multiple sites for activating mutations within the extracellular domainDefective posttranslational processing activates the tyrosine kinase encoded by the MET proto-oncogene (hepatocyte growth factor receptor).Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a.Characterization of gene expression profiles for different types of mast cells pooled from mouse stomach subregions by an RNA amplification methodGastrointestinal stromal tumor and its targeted therapeutics.Location of phosphotyrosine-containing proteins by immunocytochemistry in the rat forebrain corresponds to the distribution of the insulin receptor.Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11.c-Kit-Positive Adipose Tissue-Derived Mesenchymal Stem Cells Promote the Growth and Angiogenesis of Breast Cancer.Cytomegalovirus inhibits the engraftment of donor bone marrow cells by downregulation of hemopoietin gene expression in recipient stromaIdentification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder.Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.Candidate ligand for the c-kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors.Dendritic cell c-kit signaling and adaptive immunity: implications for the upper airways.Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo.Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors.The effect of activating mutations on dimerization, tyrosine phosphorylation and internalization of the macrophage colony stimulating factor receptor.Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase.Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal.Ligand-induced activation of chimeric receptors between the erythropoietin receptor and receptor tyrosine kinases.KIT mutations are common in testicular seminomas.Number of mast cells in the peritoneal cavity of mice: influence of microphthalmia transcription factor through transcription of newly found mast cell adhesion molecule, spermatogenic immunoglobulin superfamily.
P2860
Q22001442-9D2EE795-5E52-465E-9558-6D6C1D2AE76EQ24293012-578ECC51-DB18-4DB9-A88E-9DCB29F37363Q24533530-F1A679B6-633C-4CAC-A838-ADFF6ACDA1A5Q24610231-5CE23A0D-E023-471D-B41D-2782223A507AQ24629192-55247BD4-01ED-4D7F-AAB2-989E74C5C2CFQ24642142-2942DD34-4B46-467E-A2A0-0C3F98A862DDQ24648317-A05992DF-45C6-4EEE-A2B9-C15675B699EBQ24675202-F7CEFF4D-F202-45BF-BE54-F1D19121799BQ24685763-010E14C8-9A03-49F6-B792-66F949EB3971Q26995624-08DD41F2-D6EC-425D-890F-90C2D2004CF5Q28083779-28256217-FE57-441E-9122-D9AEDAF1141EQ28119207-C02778E4-0DA4-4A5A-8071-D6F99E320DDEQ28478611-5B04A93C-98C9-4463-826A-7FB116A5E0CAQ28569574-8AF75BCD-52D2-49A3-86A5-19C621F8F722Q28581546-A406C415-A9C7-4E77-AE63-ACCE3AF1B3F0Q28584858-B5F748AE-1EDB-4719-9779-ABB3ABA29B7EQ28587864-A28FBCA2-F753-4020-9634-79E479A1F534Q28593167-D323558D-1AA3-439B-B1A1-F794013FBE7AQ30451017-C93F06EC-4DF7-4B6E-8C70-C9EDB09D8403Q31106485-B3422C9B-571D-4CF2-AA08-D31D0B4F7404Q33238614-15A2A93A-5347-495B-ACD4-753A0C9BA85FQ33270511-E1C00F0C-DCD8-464C-8235-B1CA805A6FD2Q33401105-4743B3E6-6216-46B9-B923-908D76CB2732Q33579642-A8965D62-99ED-457C-A8B9-B2E63F3A2BB5Q33627319-282AA55D-DCB2-4F2F-B79B-3D8B135C93C1Q33719838-A7CAC26A-C89C-4A5B-81AA-3068D21065EBQ33720928-915CFFF4-1208-455B-A54E-29471E0E3D1FQ33784200-2A2DD754-1B50-47E8-A458-455AE4D06E16Q33784323-FE454C83-B899-4779-AC9A-1D71F8C021B3Q33920173-DDC43F49-8859-49E6-85D3-20004B93908FQ33922246-9DFD1AE5-D89C-4B80-9657-E50C7370E497Q34015306-2A93AAF8-C3F0-49AF-BF2E-C1E059B60E87Q34078624-C56DF2F3-E24D-48E6-A449-9CEC74C673FAQ34313642-B91998F1-D0B1-4A2E-A327-6B14CCD5B340Q34439894-95DFBE93-7762-4893-B240-97397AA22BC4Q34533831-086E9ADA-5A2A-43F5-AF2C-7D30196B35AFQ34747216-CE593689-ABC2-421F-9511-D1873048688DQ34912136-A0E7F763-F2E7-47FE-9BFA-C659C1EA4A06Q35083255-50165AD8-3EAF-40DF-B06F-46B56BF03458Q35103043-72364901-A5FB-416F-AC0B-BE4D68BD7A74
P2860
Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.
description
1988 nî lūn-bûn
@nan
1988 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Primary structure of c-kit: re ...... ellular domain and C terminus.
@ast
Primary structure of c-kit: re ...... ellular domain and C terminus.
@en
type
label
Primary structure of c-kit: re ...... ellular domain and C terminus.
@ast
Primary structure of c-kit: re ...... ellular domain and C terminus.
@en
prefLabel
Primary structure of c-kit: re ...... ellular domain and C terminus.
@ast
Primary structure of c-kit: re ...... ellular domain and C terminus.
@en
P2093
P2860
P1433
P1476
Primary structure of c-kit: re ...... cellular domain and C terminus
@en
P2093
F H Ruddle
P E Barker
P2860
P304
P356
10.1002/J.1460-2075.1988.TB02907.X
P407
P577
1988-04-01T00:00:00Z