Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy. - Wikidata - awgldk - TriplyDB

Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy.

Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy.

http://www.wikidata.org/entity/Q35112849

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Rescue of Heart Failure by Mitochondrial Recovery Electron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial Bioenergetics An experimental approach to study the function of mitochondria in cardiomyopathy Reduced activity of mtTFA decreases the transcription in mitochondria isolated from diabetic rat heart Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells.The role of mitochondrial DNA mutations in mammalian aging Defective DNA replication impairs mitochondrial biogenesis in human failing hearts Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L.ERK-mediated phosphorylation of TFAM downregulates mitochondrial transcription: implications for Parkinson's disease The strictly aerobic yeast Yarrowia lipolytica tolerates loss of a mitochondrial DNA-packaging protein.Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease.Increased mitochondrial mass in mitochondrial myopathy mice Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress Mitochondrial biogenesis and the development of diabetic retinopathy Mitochondrial Diseases Part II: Mouse models of OXPHOS deficiencies caused by defects in regulatory factors and other components required for mitochondrial function.Transcriptional control of cardiac fuel metabolism and mitochondrial function Mitochondrial energy metabolism in heart failure: a question of balance.Intracellular and extracellular ATP coordinately regulate the inverse correlation between osteoclast survival and bone resorption The PPARalpha-PGC-1alpha Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium.Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts.Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction.Frequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer.Alterations in mitochondrial function and cytosolic calcium induced by hyperglycemia are restored by mitochondrial transcription factor A in cardiomyocytes.Mouse models of mitochondrial DNA defects and their relevance for human disease.Mouse models of oxidative phosphorylation defects: powerful tools to study the pathobiology of mitochondrial diseases.Mouse models of oxidative phosphorylation dysfunction and disease Mitochondrial dysfunction in mut methylmalonic acidemia.Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic Ren2 rats PGC-1 coactivators in cardiac development and disease Mitochondrial transcription: lessons from mouse models.Mitochondria as key targets of cardioprotection in cardiac ischemic disease: role of thyroid hormone triiodothyronine.Mitochondrial DNA maintenance: an appraisal.Mitochondrial transcription in mammalian cells.Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases.Role of renin-angiotensin system in liver diseases: an outline on the potential therapeutic points of intervention.Metabolic remodelling in hypertrophied and failing myocardium: a review.Simultaneous on/off regulation of transgenes located on a mammalian chromosome with Cre-expressing adenovirus and a mutant loxP.Maintenance of respiratory chain function in mouse hearts with severely impaired mtDNA transcription.

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P2860

Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy.

http://www.wikidata.org/entity/Q35112849

description

2000 nî lūn-bûn

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2000 թուականի Մարտին հրատարակուած գիտական յօդուած

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2000 թվականի մարտին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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Genetic modification of surviv ...... mitochondrial cardiomyopathy.

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Genetic modification of surviv ...... mitochondrial cardiomyopathy.

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Genetic modification of surviv ...... mitochondrial cardiomyopathy.

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Proceedings of the National Academy of Sciences of the United States of America

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Genetic modification of surviv ...... mitochondrial cardiomyopathy.

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Duffy J

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Hansson A

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Li H

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Rustin P

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Wilhelmsson H

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P2860

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis

Mitochondrial diseases in man and mouse

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

Isolation and characterization of the mouse cardiac myosin heavy chain genes.

Revolution in mitochondrial medicine.

Mitochondrial medicine--recent advances.

Developmental regulation of myosin gene expression in mouse cardiac muscle

Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction.

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Nils-Göran Larsson

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12578067

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