Evidence that tetrodotoxin and saxitoxin act at a metal cation binding site in the sodium channels of nerve membrane. - Wikidata - awgldk - TriplyDB

Evidence that tetrodotoxin and saxitoxin act at a metal cation binding site in the sodium channels of nerve membrane.

Evidence that tetrodotoxin and saxitoxin act at a metal cation binding site in the sodium channels of nerve membrane.

http://www.wikidata.org/entity/Q35128504

about

Binding to saxitoxin to electrically excitable neuroblastoma cells.Differential effects of sulfhydryl reagents on saxitoxin and tetrodotoxin block of voltage-dependent Na channels.Competitive binding interaction between Zn2+ and saxitoxin in cardiac Na+ channels. Evidence for a sulfhydryl group in the Zn2+/saxitoxin binding site.Equilibrium binding constants for Tl+ with gramicidins A, B and C in a lysophosphatidylcholine environment determined by 205Tl nuclear magnetic resonance spectroscopy.Saxitoxin and tetrodotoxin. Electrostatic effects on sodium channel gating current in crayfish axons.Influence of negative surface charge on toxin binding to canine heart Na channels in planar bilayers.The receptor for tetrodotoxin and saxitoxin. A structural hypothesis.Large divalent cations and electrostatic potentials adjacent to membranes. Experimental results with hexamethonium.Large divalent cations and electrostatic potentials adjacent to membranes. A theoretical calculation Effects of yohimbine on squid axons Interaction between batrachotoxin and yohimbine Membrane potential dependent binding of scorpion toxin to action potential Na+ ionophore.Cooperative activation of action potential Na+ ionophore by neurotoxins.Inhibition of copper uptake in yeast reveals the copper transporter Ctr1p as a potential molecular target of saxitoxin.Use-dependent block of the voltage-gated Na(+) channel by tetrodotoxin and saxitoxin: effect of pore mutations that change ionic selectivity.Role of inactivation in local anesthetic action.Comparison of ionic selectivity of batrachotoxin-activated channels with different tetrodotoxin dissociation constants.Batrachotoxin-modified sodium channels in planar lipid bilayers. Characterization of saxitoxin- and tetrodotoxin-induced channel closures.Divalent cation competition with [3H]saxitoxin binding to tetrodotoxin-resistant and -sensitive sodium channels. A two-site structural model of ion/toxin interaction.Trimethyloxonium modification of single batrachotoxin-activated sodium channels in planar bilayers. Changes in unit conductance and in block by saxitoxin and calcium Voltage-dependent blockade of muscle Na+ channels by guanidinium toxins Extracellular protons inhibit charge immobilization in the cardiac voltage-gated sodium channel.An overview on the marine neurotoxin, saxitoxin: genetics, molecular targets, methods of detection and ecological functions.Density of sodium channels in mammalian myelinated nerve fibers and nature of the axonal membrane under the myelin sheath.The tetrodotoxin binding site is within the outer vestibule of the sodium channel.Blocking mechanisms of batrachotoxin-activated Na channels in artificial bilayers.Saxitoxin.Saxitoxin binding to the mammalian sodium channel. Competition by monovalent and divalent cations.Nonprotein neurotoxins.The kinetics of voltage-gated ion channels.Molecular model for sodium conductance and calcium transport in the squid axon.On the voltage-dependent action of tetrodotoxin Saxitoxin binding in nerves from walking legs of the lobster Homarus americanus. Two classes of receptors Single-channel studies of TTX-sensitive and TTX-resistant sodium channels in developing rat muscle reveal different open channel properties.On the mechanism by which saxitoxin binds to and blocks sodium channels.Chemistry of a Unique Polyketide-like Synthase.Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II.Immunocytochemical and physiological characterization of a population of cultured human neural precursors.A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II.Effects of saxitoxin analogues and ligand competition on sodium currents of squid axons.

P2860

Q33955228-68A35FD5-3131-4CA6-85E8-6807EE8A5201 Q34019030-BF591F82-A245-4AD5-AE57-22167B1E7C86 Q34127152-D6BBB578-9128-4778-9CC6-E6EF4C2AB182 Q34257460-385C3A1B-8B0C-4A40-B266-FBA9903CF59F Q34257494-D5DBBB54-7C7C-4943-BB92-8A0148C062CD Q34261258-366983B0-2DAC-4149-8743-76769B0F20A0 Q34271169-284B2B8F-2CB9-44F1-A95A-DA7E09669622 Q34534508-7BBA61C3-56BB-4364-8E44-B0265872FB9D Q34534522-6000E186-93DD-42F6-9783-AE1261F3EBD6 Q34656244-37946463-6C8F-43FA-946A-B947912639B6 Q34656515-FBCC7364-EB40-459E-99A8-2C605727DC39 Q35015941-CF7DDBF6-1B45-41ED-B3C8-E875900F24A4 Q35078535-FB6ACCF6-8E30-4E72-82A4-4659F4595EF9 Q35862804-FC2B417D-2F1F-440A-9AE2-F3600843E971 Q36277894-DF47E9B4-7B19-497D-83E6-AA8909582DBB Q36396080-7D430294-7D95-4628-82C0-862823301619 Q36408056-380C8D0F-DA95-4912-AFE2-5ACDECA775B7 Q36409710-4EF35556-A5E1-4CEC-AD6E-477F3C5A32B7 Q36411341-14DF088D-3C73-418E-80A6-459E564FFAAD Q36412797-0013DBB5-C5C6-4970-AB6C-16058B366342 Q36433613-C3568521-ADAB-46FF-8786-66692A401478 Q36977102-95FF8248-6D06-4109-8F17-110A8D02C7D2 Q36994197-526818FC-99C5-4E04-9FB3-7FA2CD6EEFD5 Q37598575-CDAB5752-7B04-4665-A0BF-747D599DD4DC Q37730498-24710F5A-692F-4565-B33C-A0D58B42DA46 Q38166410-31D15196-CC7D-4844-BB17-D6B4088B88EF Q38207566-82C7E0EF-D5F2-419A-AF81-480D03826239 Q39222063-5460FF5F-07A1-4F51-B8B7-6B780F70BF62 Q40319786-C9B3DE8A-4A4C-4914-BBA7-C5B492BE35C7 Q40401722-517D01CF-4189-49F4-BDE7-658DE5B28476 Q41044916-F7EB0688-F530-4A92-AF1F-4E2BE415F196 Q41912807-F089DC74-F5A2-402E-B3A9-955AA27CC297 Q42139036-0C157803-90C7-4597-B802-69AD47D56F94 Q44013537-431F9C5B-49FD-418D-A308-7CA8C4B5D00B Q48423180-64E7B1AA-30C4-4E9D-8206-1FC64A263167 Q49488740-E0589B06-DA9D-493E-9E21-67553D0B9938 Q50796508-1D94F430-FE9C-4B7C-A769-0E4F9BC9682F Q51391450-02AA8BEE-BFFE-45F0-A187-E521ADC131B3 Q51744647-EA4DB74A-DD52-4790-AFA0-EBF7595C4829 Q51806107-13007ED2-AA98-4BFE-AA41-FAFF429FABEC

P2860

Evidence that tetrodotoxin and saxitoxin act at a metal cation binding site in the sodium channels of nerve membrane.

http://www.wikidata.org/entity/Q35128504

description

1974 nî lūn-bûn

@nan

1974 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1974 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1974年の論文

@ja

1974年論文

@yue

1974年論文

@zh-hant

1974年論文

@zh-hk

1974年論文

@zh-mo

1974年論文

@zh-tw

1974年论文

@wuu

name

Evidence that tetrodotoxin and ...... um channels of nerve membrane.

@ast

Evidence that tetrodotoxin and ...... um channels of nerve membrane.

@en

type

label

Evidence that tetrodotoxin and ...... um channels of nerve membrane.

@ast

Evidence that tetrodotoxin and ...... um channels of nerve membrane.

@en

prefLabel

Evidence that tetrodotoxin and ...... um channels of nerve membrane.

@ast

Evidence that tetrodotoxin and ...... um channels of nerve membrane.

@en

P1433

Q35128504-FB3B07AC-3D85-4EE7-8E7B-ED6D3E085B32

P1476

Q35128504-31F277A5-169A-4186-B318-820CE6E55A66

P2093

Q35128504-12E7FF6B-58BA-4884-90AD-56F4198FA397

Q35128504-7691A140-0E33-447D-9053-B88854447F36

Q35128504-C4D2E79A-D152-490D-99AF-2398792EA81C

P2860

Q35128504-0F4874ED-74BB-4041-B5E2-4ACAAC635E3F

Q35128504-2385BBE8-2595-463F-A0A4-EC3C88382BD9

Q35128504-2E20187B-C07F-409C-A3E4-20942868A10B

Q35128504-343E3D5D-D88A-414F-8D06-21BB512383EA

Q35128504-38541A35-4D16-4CA2-804E-C05225B9A1CF

Q35128504-495B474D-4D9C-4AB6-8A51-D8FFB78564D9

Q35128504-5AADE2AF-B4E6-4AB6-A578-DE23F1886E6E

Q35128504-5F84F948-961F-41A8-A553-9B7DF482BF34

Q35128504-740A4CE2-7325-4E5D-AC5B-8AA102E9DBDC

Q35128504-84AB0EB9-6FB1-4E7F-B325-23A1AEC2B868

P304

Q35128504-237DD8DE-C1EF-4237-9ABB-39FA58C63597

P31

Q35128504-6E794F79-C2F0-4334-83F3-0C551B2AD28D

P356

Q35128504-D8A001A7-D9C3-47B6-A6AE-344873E26C86

P407

Q35128504-056D5AED-354D-4A7E-BC8E-7787A8EB98EF

P433

Q35128504-1B4C9780-6243-48FE-9D30-752B6D1C1447

P478

Q35128504-B46A5EC2-B24E-4CB0-81E0-A5A7EA69ADA2

P577

Q35128504-DD9D5576-7BD9-4F3B-876F-A282F64F846F

P5875

Q35128504-8F20BDF3-CF4E-4FCA-A5B4-151B2A0C9A75

P698

Q35128504-37E52C35-7188-420D-ABC5-20BEC9E7CF46

P932

Q35128504-30CC77A0-70FC-4FCF-A07F-340765E5EBEB

P356

PNAS.71.10.3936

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Evidence that tetrodotoxin and ...... um channels of nerve membrane.

@en

P2093

Henderson R

http://www.w3.org/2001/XMLSchema#string

Ritchie JM

http://www.w3.org/2001/XMLSchema#string

Strichartz GR

http://www.w3.org/2001/XMLSchema#string

P2860

Tetrodotoxin, saxitoxin and their significance in the study of excitation phenomena.

Sodium uptake associated with activation of action potential ionophores of cultured neuroblastoma and muscle cells

The permeability of the sodium channel to metal cations in myelinated nerve.

Ionic blockage of sodium channels in nerve.

Divalent ions and the surface potential of charged phospholipid membranes

Partial characterization of a tetrodotoxin-binding component from nerve membrane.

Charges and potentials at the nerve surface. Divalent ions and pH.

The permeability of the sodium channel to organic cations in myelinated nerve.

Pharmacological modifications of the sodium channels of frog nerve.

The binding of labelled saxitoxin to the sodium channels in nerve membranes.

P304

3936-3940

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.71.10.3936

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

71

http://www.w3.org/2001/XMLSchema#string

P577

1974-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

18636367

http://www.w3.org/2001/XMLSchema#string

P698

4530274

http://www.w3.org/2001/XMLSchema#string

P932

434301

http://www.w3.org/2001/XMLSchema#string