The Hsp90 cochaperone p23 is essential for perinatal survival. - Wikidata - awgldk - TriplyDB

The Hsp90 cochaperone p23 is essential for perinatal survival.

The Hsp90 cochaperone p23 is essential for perinatal survival.

http://www.wikidata.org/entity/Q35131651

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High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance Chaperoning steroidal physiology: lessons from mouse genetic models of Hsp90 and its cochaperones The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse The p23 molecular chaperone and GCN5 acetylase jointly modulate protein-DNA dynamics and open chromatin status The aryl hydrocarbon receptor complex and the control of gene expression cPGES/p23 is required for glucocorticoid receptor function and embryonic growth but not prostaglandin E2 synthesis Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation.The helix 1-3 loop in the glucocorticoid receptor LBD is a regulatory element for FKBP cochaperones.Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23 The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.Prostaglandin E2 synthases in neurologic homeostasis and disease Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23.Influenza virus infection induces the nuclear relocalization of the Hsp90 co-chaperone p23 and inhibits the glucocorticoid receptor response.Characterization of plant p23-like proteins for their co-chaperone activities Control of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1L Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment.The Aryl-hydrocarbon receptor does not require the p23 co-chaperone for ligand binding and target gene expression in vivo.A network of its own: the unique interactome of the Hsp90 cochaperone, Sba1/p23 Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis Co-chaperone p23 regulates C. elegans Lifespan in Response to Temperature.Management of cytoskeleton architecture by molecular chaperones and immunophilins.The co-chaperone p23 promotes prostate cancer motility and metastasis Caspase-7: a critical mediator of optic nerve injury-induced retinal ganglion cell death Functioning of the Hsp90 machine in chaperoning checkpoint kinase I (Chk1) and the progesterone receptor (PR).Gedunin inactivates the co-chaperone p23 protein causing cancer cell death by apoptosis.p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity Minireview: the intersection of steroid receptors with molecular chaperones: observations and questions Plasticity of the Hsp90 chaperone machine in divergent eukaryotic organisms.Molecular chaperones as regulators of cell death.Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness.Nox5 stability and superoxide production is regulated by C-terminal binding of Hsp90 and CO-chaperones.Transgenic overexpression of p23 induces spontaneous hydronephrosis in mice.Mechanisms of Resistance to Hsp90 Inhibitor Drugs: A Complex Mosaic Emerges.Cytosolic Bax: does it require binding proteins to keep its pro-apoptotic activity in check?Signal responsiveness of IkappaB kinases is determined by Cdc37-assisted transient interaction with Hsp90.Global functional map of the p23 molecular chaperone reveals an extensive cellular network.Prostaglandin terminal synthases as novel therapeutic targets.Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies.The FKBP51 Glucocorticoid Receptor Co-Chaperone: Regulation, Function, and Implications in Health and Disease.Evidence for Hsp90 Co-chaperones in Regulating Hsp90 Function and Promoting Client Protein Folding.

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P2860

The Hsp90 cochaperone p23 is essential for perinatal survival.

http://www.wikidata.org/entity/Q35131651

description

2006 nî lūn-bûn

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2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

The Hsp90 cochaperone p23 is essential for perinatal survival.

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The Hsp90 cochaperone p23 is essential for perinatal survival.

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type

label

The Hsp90 cochaperone p23 is essential for perinatal survival.

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The Hsp90 cochaperone p23 is essential for perinatal survival.

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prefLabel

The Hsp90 cochaperone p23 is essential for perinatal survival.

@ast

The Hsp90 cochaperone p23 is essential for perinatal survival.

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Molecular and Cellular Biology

P1476

The Hsp90 cochaperone p23 is essential for perinatal survival

@en

P2093

Didier Picard

http://www.w3.org/2001/XMLSchema#string

Gary W Hoyle

http://www.w3.org/2001/XMLSchema#string

Patricia Ruiz

http://www.w3.org/2001/XMLSchema#string

Sara M Ludwig

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Thomas Floss

http://www.w3.org/2001/XMLSchema#string

Wolfgang Wurst

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P2860

B-ind1, a novel mediator of Rac1 signaling cloned from sodium butyrate-treated fibroblasts

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

Disassembly of transcriptional regulatory complexes by molecular chaperones

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D

Genetic and biochemical analysis of p23 and ansamycin antibiotics in the function of Hsp90-dependent signaling proteins

The identification of Wos2, a p23 homologue that interacts with Wee1 and Cdc2 in the mitotic control of fission yeasts

The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding

The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies

Altered stability of pulmonary surfactant in SP-C-deficient mice

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8976-8983

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scholarly article

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10.1128/MCB.00734-06

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23

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26

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2006-09-25T00:00:00Z

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17000766

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1636834

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