Molecular and cellular pharmacology of the novel noncamptothecin topoisomerase I inhibitor Genz-644282.
about
Drugging topoisomerases: lessons and challengesDevelopment and validation of an immunoassay for quantification of topoisomerase I in solid tumor tissuesIdentification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase IThe dual topoisomerase inhibitor A35 preferentially and specially targets topoisomerase 2α by enhancing pre-strand and post-strand cleavage and inhibiting DNA religationSophoridinol derivative 05D induces tumor cells apoptosis by topoisomerase1-mediated DNA breakageOptimization of the lactam side chain of 7-azaindenoisoquinoline topoisomerase I inhibitors and mechanism of action studies in cancer cells.An overview of quinoline as a privileged scaffold in cancer drug discovery.Camptothecin (CPT) and its derivatives are known to target topoisomerase I (Top1) as their mechanism of action: did we miss something in CPT analogue molecular targets for treating human disease such as cancer?
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P2860
Molecular and cellular pharmacology of the novel noncamptothecin topoisomerase I inhibitor Genz-644282.
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2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Molecular and cellular pharmac ...... erase I inhibitor Genz-644282.
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Molecular and cellular pharmac ...... erase I inhibitor Genz-644282.
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Molecular and cellular pharmac ...... erase I inhibitor Genz-644282.
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Molecular and cellular pharmac ...... erase I inhibitor Genz-644282.
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Molecular and cellular pharmac ...... erase I inhibitor Genz-644282.
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Molecular and cellular pharmac ...... erase I inhibitor Genz-644282.
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P2093
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Molecular and cellular pharmac ...... erase I inhibitor Genz-644282.
@en
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Beverly A Teicher
Dhriti Sooryakumar
Thomas S Dexheimer
P2860
P304
P356
10.1158/1535-7163.MCT-10-1043
P50
P577
2011-06-02T00:00:00Z