The striatum is highly susceptible to mitochondrial oxidative phosphorylation dysfunctions
about
Mouse models of Parkinson's disease associated with mitochondrial dysfunctionMitochondrial genome changes and neurodegenerative diseasesEndogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic StressShaping the role of mitochondria in the pathogenesis of Huntington's diseaseA defect in the mitochondrial complex III, but not complex IV, triggers early ROS-dependent damage in defined brain regions.High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function.Topological length of white matter connections predicts their rate of atrophy in premanifest Huntington's disease.Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formationDifferential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction.Long-term bezafibrate treatment improves skin and spleen phenotypes of the mtDNA mutator mouse.Acute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons.The use of mitochondria-targeted endonucleases to manipulate mtDNAGenome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum.Somatic mtDNA mutation spectra in the aging human putamen.Mitochondrial Diseases Part II: Mouse models of OXPHOS deficiencies caused by defects in regulatory factors and other components required for mitochondrial function.Mechanisms linking mtDNA damage and aging.Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse.Cumulative mtDNA damage and mutations contribute to the progressive loss of RGCs in a rat model of glaucomaStriatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's diseaseMitochondrial mutations and polymorphisms in psychiatric disorders.Mitochondrial disease: mtDNA and protein segregation mysteries in iPSCsMitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stressTransient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell poolMorphometric and volumetric study of caudate and putamen nuclei in normal individuals by MRI: Effect of normal aging, gender and hemispheric differences.Metabolite measurements in the caudate nucleus, anterior cingulate cortex and hippocampus among patients with mitochondrial disorders: a case-control study using proton magnetic resonance spectroscopy.Rodent models and contemporary molecular techniques: notable feats yet incomplete explanations of Parkinson's disease pathogenesis.A synopsis on aging-Theories, mechanisms and future prospects.Study of normal volumetric variation in the putamen with age and sex using magnetic resonance imaging.A Study of volumetric variations of basal nuclei in the normal human brain by magnetic resonance imaging.Connexin hemichannel blockade improves survival of striatal GABA-ergic neurons after global cerebral ischaemia in term-equivalent fetal sheep.3-Nitropropionic acid modifies neurotrophin mRNA expression in the mouse striatum: 18S-rRNA is a reliable control gene for studies of the striatum.Cytochrome c oxidase deficit is associated with the seizure onset zone in young patients with focal cortical dysplasia Type II.LKB1-regulated adaptive mechanisms are essential for neuronal survival following mitochondrial dysfunction.Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner.Mitochondrial susceptibility in a model of paraquat neurotoxicity.Impairment of striatal mitochondrial function by acute paraquat poisoning.Lack of Parkin anticipates the phenotype and affects mitochondrial morphology and mtDNA levels in a mouse model of Parkinson's Disease.Differential susceptibility of striatal, hippocampal and cortical neurons to Caspase-6.AGC1-malate aspartate shuttle activity is critical for dopamine handling in the nigrostriatal pathway.Striatal Mitochondrial Disruption following Severe Traumatic Brain Injury.
P2860
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P2860
The striatum is highly susceptible to mitochondrial oxidative phosphorylation dysfunctions
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The striatum is highly suscept ...... e phosphorylation dysfunctions
@ast
The striatum is highly suscept ...... e phosphorylation dysfunctions
@en
type
label
The striatum is highly suscept ...... e phosphorylation dysfunctions
@ast
The striatum is highly suscept ...... e phosphorylation dysfunctions
@en
prefLabel
The striatum is highly suscept ...... e phosphorylation dysfunctions
@ast
The striatum is highly suscept ...... e phosphorylation dysfunctions
@en
P2093
P2860
P1476
The striatum is highly suscept ...... e phosphorylation dysfunctions
@en
P2093
Alicia M Pickrell
Carlos T Moraes
Hirokazu Fukui
Milena Pinto
P2860
P304
P356
10.1523/JNEUROSCI.6223-10.2011
P407
P577
2011-07-01T00:00:00Z