Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease
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Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's DiseaseMouse models of Parkinson's disease associated with mitochondrial dysfunctionAgeing and Parkinson's disease: why is advancing age the biggest risk factor?Mitochondrial genome changes and neurodegenerative diseasesPioglitazone ameliorates the phenotype of a novel Parkinson's disease mouse model by reducing neuroinflammationEndogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic StressMitochondrial defects and oxidative stress in Alzheimer disease and Parkinson diseaseThe mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stressMitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formationPentazocine Protects SN4741 Cells Against MPP+-Induced Cell Damage via Up-Regulation of the Canonical Wnt/β-Catenin Signaling Pathway.Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's diseaseExposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegansThe use of mitochondria-targeted endonucleases to manipulate mtDNAAccumulation of mitochondrial DNA deletions within dopaminergic neurons triggers neuroprotective mechanisms.The role of mitochondrial DNA mutation on neurodegenerative diseases.Compensatory mechanisms in genetic models of neurodegeneration: are the mice better than humans?Mitochondrial Diseases Part II: Mouse models of OXPHOS deficiencies caused by defects in regulatory factors and other components required for mitochondrial function.Delayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's diseaseCumulative mtDNA damage and mutations contribute to the progressive loss of RGCs in a rat model of glaucomaMitochondrial retrograde signaling regulates neuronal functionParkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress.Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit.Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice.The angiotensin converting enzyme inhibitor captopril protects nigrostriatal dopamine neurons in animal models of parkinsonismThe impact of mitochondrial DNA and nuclear genes related to mitochondrial functioning on the risk of Parkinson's disease.Engrailed signaling in axon guidance and neuron survival.Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences.The centrality of mitochondria in the pathogenesis and treatment of Parkinson's disease.The Parkinson Disease Mitochondrial Hypothesis: Where Are We at?Dissecting the role of Engrailed in adult dopaminergic neurons--Insights into Parkinson disease pathogenesisParkinson's disease: diagnostic utility of volumetric imaging.Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease.The challenge in translating basic research discoveries to treatment of Huntington disease.Lack of Parkin anticipates the phenotype and affects mitochondrial morphology and mtDNA levels in a mouse model of Parkinson's Disease.Parkinson's disease: experimental models and reality.Mitochondrial DNA Double-Strand Breaks in Oligodendrocytes Cause Demyelination, Axonal Injury, and CNS Inflammation.Mitochondrial retrograde signaling in the nervous system.Morinda citrifolia mitigates rotenone-induced striatal neuronal loss in male Sprague-Dawley rats by preventing mitochondrial pathway of intrinsic apoptosis.Effects of mild running on substantia nigra during early neurodegeneration.
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P2860
Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Striatal dysfunctions associat ...... e model of Parkinson's disease
@ast
Striatal dysfunctions associat ...... e model of Parkinson's disease
@en
type
label
Striatal dysfunctions associat ...... e model of Parkinson's disease
@ast
Striatal dysfunctions associat ...... e model of Parkinson's disease
@en
prefLabel
Striatal dysfunctions associat ...... e model of Parkinson's disease
@ast
Striatal dysfunctions associat ...... e model of Parkinson's disease
@en
P2860
P921
P1476
Striatal dysfunctions associat ...... e model of Parkinson's disease
@en
P2093
Aline Hida
Carlos T Moraes
P2860
P304
17649-17658
P356
10.1523/JNEUROSCI.4871-11.2011
P407
P577
2011-11-01T00:00:00Z