WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts.
about
Specific small molecule inhibitors of Skp2-mediated p27 degradationOverexpression of miR-584-5p inhibits proliferation and induces apoptosis by targeting WW domain-containing E3 ubiquitin protein ligase 1 in gastric cancer.PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signalingWWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells.MiR-21 suppresses endothelial progenitor cell proliferation by activating the TGFβ signaling pathway via downregulation of WWP1.NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation.Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma.Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet-Induced Kidney Disease.SIRT6 delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation.Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors.The ubiquitin proteasome system in Caenorhabditis elegans and its regulation.WWP1: a versatile ubiquitin E3 ligase in signaling and diseases.p27T187A knockin identifies Skp2/Cks1 pocket inhibitors for advanced prostate cancer.UPS Activation in the Battle Against Aging and Aggregation-Related Diseases: An Extended Review.FOXQ1 regulates senescence-associated inflammation via activation of SIRT1 expressionKnockdown of WWP1 inhibits growth and invasion, but induces apoptosis of osteosarcoma cells.Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia.WWP1 as a potential tumor oncogene regulates PTEN-Akt signaling pathway in human gastric carcinoma.
P2860
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P2860
WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
WW domain-containing E3 ubiqui ...... in human diploid fibroblasts.
@ast
WW domain-containing E3 ubiqui ...... in human diploid fibroblasts.
@en
type
label
WW domain-containing E3 ubiqui ...... in human diploid fibroblasts.
@ast
WW domain-containing E3 ubiqui ...... in human diploid fibroblasts.
@en
prefLabel
WW domain-containing E3 ubiqui ...... in human diploid fibroblasts.
@ast
WW domain-containing E3 ubiqui ...... in human diploid fibroblasts.
@en
P2093
P2860
P356
P1476
WW domain-containing E3 ubiqui ...... in human diploid fibroblasts.
@en
P2093
Lixiang Xue
Tanjun Tong
Tianda Chen
Xiaoxiao Cao
P2860
P304
33447-33456
P356
10.1074/JBC.M111.225565
P407
P577
2011-07-27T00:00:00Z