TMEM106B a novel risk factor for frontotemporal lobar degeneration - Wikidata - awgldk - TriplyDB

TMEM106B a novel risk factor for frontotemporal lobar degeneration

TMEM106B a novel risk factor for frontotemporal lobar degeneration

http://www.wikidata.org/entity/Q35512313

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Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders Mechanisms of granulin deficiency: lessons from cellular and animal models TMEM106B expression is reduced in Alzheimer's disease brains Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.TMEM106B, a frontotemporal lobar dementia (FTLD) modifier, associates with FTD-3-linked CHMP2B, a complex of ESCRT-III.The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum Progranulin: an emerging target for FTLD therapies.C9ORF72 hexanucleotide repeats in behavioral and motor neuron disease: clinical heterogeneity and pathological diversity.The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function.TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in Han Chinese.TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins.

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TMEM106B a novel risk factor for frontotemporal lobar degeneration

http://www.wikidata.org/entity/Q35512313

description

2011 nî lūn-bûn

@nan

2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

TMEM106B a novel risk factor for frontotemporal lobar degeneration

@ast

TMEM106B a novel risk factor for frontotemporal lobar degeneration

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type

label

TMEM106B a novel risk factor for frontotemporal lobar degeneration

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TMEM106B a novel risk factor for frontotemporal lobar degeneration

@en

prefLabel

TMEM106B a novel risk factor for frontotemporal lobar degeneration

@ast

TMEM106B a novel risk factor for frontotemporal lobar degeneration

@en

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Journal of Molecular Neuroscience

P1476

TMEM106B a novel risk factor for frontotemporal lobar degeneration

@en

P2860

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Genome-wide association study reveals genetic risk underlying Parkinson's disease

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

Pedigree with frontotemporal lobar degeneration--motor neuron disease and Tar DNA binding protein-43 positive neuropathology: genetic linkage to chromosome 9.

Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family.

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels.

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s12031-011-9555-x

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scholarly article

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3

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Christine Van Broeckhoven

Julie van der Zee

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2011-05-26T00:00:00Z

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2011-11-01T00:00:00Z

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51167129

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21614538

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Frontotemporal lobar degeneration

membrane proteins

nerve tissue proteins

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3207134

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