TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers. - Wikidata - awgldk - TriplyDB

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

http://www.wikidata.org/entity/Q34555400

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The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders Frontotemporal Lobar Degeneration and MicroRNAs Phenotypic Heterogeneity of Monogenic Frontotemporal Dementia Potential mechanisms of progranulin-deficient FTLD Therapeutic and diagnostic challenges for frontotemporal dementia Progranulin: at the interface of neurodegenerative and metabolic diseases Frontotemporal dementia: a bridge between dementia and neuromuscular disease Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling.TMEM106B expression is reduced in Alzheimer's disease brains Genetics of dementia.Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72 TDP-43 in aging and Alzheimer's disease - a review Genome-wide association studies in neurology.Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains.The TMEM106B locus and TDP-43 pathology in older persons without FTLD Allelic expression of deleterious protein-coding variants across human tissues.Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine.TMEM106B a novel risk factor for frontotemporal lobar degeneration Differential clinicopathologic and genetic features of late-onset amnestic dementias Similar clinical and neuroimaging features in monozygotic twin pair with mutation in progranulin.Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program.TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways.TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum Advances in understanding the molecular basis of frontotemporal dementia.Progranulin: an emerging target for FTLD therapies.The role of the innate immune system in Alzheimer's disease and frontotemporal lobar degeneration: an eye on microglia.TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia.Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease.Novel progranulin mutations with reduced serum-progranulin levels in frontotemporal lobar degeneration.Epidemiology and genetics of frontotemporal dementia: a door-to-door survey in southern Italy.Progranulin Levels in Plasma and Cerebrospinal Fluid in Granulin Mutation Carriers.Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain.Promoter DNA methylation regulates progranulin expression and is altered in FTLD.

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P2860

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

http://www.wikidata.org/entity/Q34555400

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

TMEM106B regulates progranulin ...... FTLD in GRN mutation carriers.

@ast

TMEM106B regulates progranulin ...... FTLD in GRN mutation carriers.

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TMEM106B regulates progranulin ...... FTLD in GRN mutation carriers.

@nl

type

label

TMEM106B regulates progranulin ...... FTLD in GRN mutation carriers.

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TMEM106B regulates progranulin ...... FTLD in GRN mutation carriers.

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TMEM106B regulates progranulin ...... FTLD in GRN mutation carriers.

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prefLabel

TMEM106B regulates progranulin ...... FTLD in GRN mutation carriers.

@ast

TMEM106B regulates progranulin ...... FTLD in GRN mutation carriers.

@en

TMEM106B regulates progranulin ...... FTLD in GRN mutation carriers.

@nl

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