Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels. - Wikidata - awgldk - TriplyDB

Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels.

Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels.

http://www.wikidata.org/entity/Q34959322

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Exome-sequencing confirms DNAJC5 mutations as cause of adult neuronal ceroid-lipofuscinosis Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes The genetics and neuropathology of frontotemporal lobar degeneration Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders Phenotypic Heterogeneity of Monogenic Frontotemporal Dementia Mechanisms of granulin deficiency: lessons from cellular and animal models Therapeutic and diagnostic challenges for frontotemporal dementia Potential roles of microglial cell progranulin in HIV-associated CNS pathologies and neurocognitive impairment Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study.TMEM106B expression is reduced in Alzheimer's disease brains Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia.Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis The TMEM106B locus and TDP-43 pathology in older persons without FTLD Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine.TMEM106B a novel risk factor for frontotemporal lobar degeneration Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.A novel Alzheimer disease locus located near the gene encoding tau protein.TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways.Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort.The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum Advances in understanding the molecular basis of frontotemporal dementia.Progranulin: an emerging target for FTLD therapies.TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia.Novel progranulin mutations with reduced serum-progranulin levels in frontotemporal lobar degeneration.Progranulin Levels in Plasma and Cerebrospinal Fluid in Granulin Mutation Carriers.A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain.Increased expression of the frontotemporal dementia risk factor TMEM106B causes C9orf72-dependent alterations in lysosomes.Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia.TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.Human genetics as a tool to identify progranulin regulators.Progranulin axis and recent developments in frontotemporal lobar degeneration Effects of Multiple Genetic Loci on Age at Onset in Frontotemporal Dementia.Genetics of FTLD: overview and what else we can expect from genetic studies.The clinical spectrum of sporadic and familial forms of frontotemporal dementia.

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Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels.

http://www.wikidata.org/entity/Q34959322

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Association of TMEM106B gene p ...... lasma granulin protein levels.

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Association of TMEM106B gene p ...... lasma granulin protein levels.

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Association of TMEM106B gene p ...... lasma granulin protein levels.

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type

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Association of TMEM106B gene p ...... lasma granulin protein levels.

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Association of TMEM106B gene p ...... lasma granulin protein levels.

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Association of TMEM106B gene p ...... lasma granulin protein levels.

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Association of TMEM106B gene p ...... lasma granulin protein levels.

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Association of TMEM106B gene p ...... lasma granulin protein levels.

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Association of TMEM106B gene p ...... lasma granulin protein levels.

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Association of TMEM106B gene p ...... lasma granulin protein levels.

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Anthony L Hinrichs

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Huei-Hsin Chiang

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Joanne B Norton

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Jun Wang

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Kevin Mayo

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Noah Spiegel

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Sarah Bertelsen

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Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

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581-586

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10.1001/ARCHNEUROL.2010.350

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5

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68

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Carlos Cruchaga

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49742241

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