Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
about
Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicaseNucleotide excision repair of a DNA interstrand cross-link produces single- and double-strand breaks.DNA damage and interstrand cross-link formation upon irradiation of aryl iodide C-nucleotide analoguesBiological properties of single chemical-DNA adducts: a twenty year perspectiveProtein binding has a large effect on radical mediated DNA damage.Reactivity of Nucleic Acid Radicals.Intrastrand G-U cross-links generated by the oxidation of guanine in 5'-d(GCU) and 5'-r(GCU).Mechanisms of free radical-induced damage to DNA.Photoswitchable formation of a DNA interstrand cross-link by a coumarin-modified nucleotide.Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy.Radiosensitization by a modified nucleotide that produces DNA interstrand cross-links under hypoxic conditions.Probing interactions between lysine residues in histone tails and nucleosomal DNA via product and kinetic analysis.Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.A simple, high-yield synthesis of DNA duplexes containing a covalent, thermally cleavable interstrand cross-link at a defined locationOxidation of single-stranded oligonucleotides by carbonate radical anions: generating intrastrand cross-links between guanine and thymine bases separated by cytosinesHypoxia-selective DNA interstrand cross-link formation by two modified nucleosidesROS-inducible DNA cross-linking agent as a new anticancer prodrug building block.Facile SNP detection using bifunctional, cross-linking oligonucleotide probesElucidating DNA damage and repair processes by independently generating reactive and metastable intermediates.Interstrand cross-link formation in duplex and triplex DNA by modified pyrimidinesBromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases.Oxidation and reduction of the 5-(2'-deoxyuridinyl)methyl radicalMultinuclear NMR and kinetic analysis of DNA interstrand cross-link formation.Simple, High-Yield Syntheses of DNA Duplexes Containing Interstrand DNA-DNA Cross-Links Between an N(4) -Aminocytidine Residue and an Abasic SitePhotochemical control of DNA structure through radical disproportionation.Deconvoluting the reactivity of two intermediates formed from modified pyrimidines.Scope and mechanism of interstrand cross-link formation by the C4'-oxidized abasic site.DNA interstrand cross-linking upon irradiation of aryl halide C-nucleotides.Induced cross-linking reactions to target genes using modified oligonucleotides.Photo-triggered fluorescent theranostic prodrugs as DNA alkylating agents for mechlorethamine release and spatiotemporal monitoring.A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites.Fluoride as an inducible DNA cross-linking agent for new antitumor prodrug.5-Phenylselenyl- and 5-methylselenyl-methyl-2'-deoxyuridine induce oxidative stress, DNA damage, and caspase-2-dependent apoptosis in cancer cells.Photochemical Generation of Benzyl Cations That Selectively Cross-Link Guanine and Cytosine in DNA.Aromatic nitrogen mustard-based prodrugs: activity, selectivity, and the mechanism of DNA cross-linking.The development of ruthenium(ii) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications.
P2860
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P2860
Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
@ast
Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
@en
type
label
Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
@ast
Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
@en
prefLabel
Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
@ast
Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
@en
P2093
P2860
P356
P1476
Oxygen independent DNA interstrand cross-link formation by a nucleotide radical.
@en
P2093
In Seok Hong
Marc M Greenberg
P2860
P304
P356
10.1021/JA0563657
P407
P577
2006-01-01T00:00:00Z