p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment - Wikidata - awgldk - TriplyDB

p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment

p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment

http://www.wikidata.org/entity/Q35551712

about

The multifaceted roles of the HORMA domain in cellular signaling TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response Effect of Cell Shape and Dimensionality on Spindle Orientation and Mitotic Timing The APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.Spatiotemporal regulation of the anaphase-promoting complex in mitosis The spindle assembly checkpoint works like a rheostat rather than a toggle switch Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.The kinetochore Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31(comet).Thyroid hormone receptor interacting protein 13 (TRIP13) AAA-ATPase is a novel mitotic checkpoint-silencing protein Cohesion fatigue explains why pharmacological inhibition of the APC/C induces a spindle checkpoint-dependent mitotic arrest TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching Role of phosphorylation of Cdc20 in p31(comet)-stimulated disassembly of the mitotic checkpoint complex Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation Systematic dissection of dynein regulators in mitosis Phosphorylation of Xenopus p31(comet) potentiates mitotic checkpoint exit.Monopolar spindle 1 (MPS1) kinase promotes production of closed MAD2 (C-MAD2) conformer and assembly of the mitotic checkpoint complex Coordinated regulation of p31(Comet) and Mad2 expression is required for cellular proliferation Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.Panta rhei: the APC/C at steady state.Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling.Phosphorylation regulates the p31Comet-mitotic arrest-deficient 2 (Mad2) interaction to promote spindle assembly checkpoint (SAC) activity.A Dynamical Model for Activating and Silencing the Mitotic Checkpoint The mitotic checkpoint complex (MCC): looking back and forth after 15 years.Mitotic Checkpoint Regulators Control Insulin Signaling and Metabolic Homeostasis.Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation p31(comet) inactivates the chemically induced Mad2-dependent spindle assembly checkpoint and leads to resistance to anti-mitotic drugs.

P2860

Q26776388-9A52399A-DAC3-4821-80A2-E727A8E6529C Q27309241-E5117317-A958-4498-97DD-D33C7E503AD5 Q27313451-E4D056CD-F515-40EA-9AB3-D880B4CCDD42 Q27932569-AA5B8792-3DCD-416C-95A1-9C8CCAFF0586 Q28081253-F11043D2-5A34-4E39-AF8C-6BC2CCE30031 Q30557537-D957E061-7C49-42B4-A8C0-C389DF376A25 Q30667509-3EACA947-2081-4AF0-8F4C-569D336A08CD Q33796368-E9DD4EB8-0259-4D36-8CAB-C1152066A98B Q34082645-37C37E64-FA3A-4655-8EDB-F5A2166F2013 Q34140924-EF2A7276-B7DF-433A-A1E7-3DCE5B8186E8 Q34473920-BB0D4E7D-16E7-4DE5-BA92-25CD7541DB5B Q35616366-BC520169-BFED-4CF5-88D6-E0009FAB0173 Q35991476-A7C4ABB6-A6A6-471C-BE7D-FEFA70DF7C13 Q36289100-DBCF0449-803C-4504-9A81-EDC8CFA6D980 Q36772612-9437853D-7946-4521-ABA5-E2E529D0D19C Q36781122-FB1A9E61-9C6C-4B91-BAD5-4E78741F3A4A Q37368640-9DFDABA7-6038-46A5-8A0E-9009C9306EFF Q37525854-33A03375-679F-41A4-B4C4-A7B4B36C9107 Q38025305-6CDEAE7B-AA65-4449-BF03-3BE77C01D38B Q38099298-1F62D756-28D8-47BB-8FBB-C02DB1774F37 Q38893872-26561142-78A6-4373-9D16-5D5FF235B43D Q39998109-3D0C1E2C-908F-4D8C-8592-8EA425921C22 Q41081399-19637769-A88E-4118-B0DD-EF4AE604CD6D Q41146841-435B39F9-F5DE-43BE-B812-5FA96ADF535B Q41440478-714C27E8-5F49-4F5A-9EE5-C25D6B32C7A9 Q42207747-22B270EB-0936-4C36-89F5-04817753864F Q42911667-D9F5B3D1-032B-4A5B-BA49-0D90B218717F

P2860

p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment

http://www.wikidata.org/entity/Q35551712

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

p31(comet) acts to ensure time ...... uent to kinetochore attachment

@ast

p31(comet) acts to ensure time ...... uent to kinetochore attachment

@en

type

label

p31(comet) acts to ensure time ...... uent to kinetochore attachment

@ast

p31(comet) acts to ensure time ...... uent to kinetochore attachment

@en

prefLabel

p31(comet) acts to ensure time ...... uent to kinetochore attachment

@ast

p31(comet) acts to ensure time ...... uent to kinetochore attachment

@en

P1433

Q35551712-EF1335EE-C0A0-4DC0-A1EC-6C85A5910D9F

P1476

Q35551712-0EA87B52-309F-4F14-8A64-E49098E8545B

P2093

Q35551712-010A40E1-8157-4325-AD80-42756A9C3E69

Q35551712-1072F2E5-3F27-45FD-87E9-3FAB5453E733

Q35551712-7A11B605-CCD5-4848-9128-01AC8312B4BD

Q35551712-8B9659E3-3294-4C7F-BCA1-F6CF690CA4A1

Q35551712-A1C310A6-4809-48B8-BAD5-93A0B32BD9EF

P2860

Q35551712-12072E0A-3294-49C7-968D-FCF13159427F

Q35551712-18FE02FA-A337-4598-9135-AB4F0007F394

Q35551712-198DFABB-F72E-4070-95F8-6640C78C9B79

Q35551712-1EDE11DE-1F79-4189-B2D2-01EC097D846C

Q35551712-203F2129-F5EC-4EAA-A17E-9A7163B4FC61

Q35551712-226FCC7D-9843-4547-B8D1-A3342931918E

Q35551712-2A6650F2-0032-4694-9067-4AE2E8692EB6

Q35551712-2A86384A-A1D9-46A2-8A6E-805FF60C5B91

Q35551712-3088C8A8-E7E5-4D0D-857C-D8E7700A3215

Q35551712-3404487F-3FC2-4395-8105-2C62592FFF1B

P304

Q35551712-99E4ACA9-690C-481E-A95A-B6EE4ABE4C80

P31

Q35551712-C1554BDA-ACEF-4E73-8835-99C52AAD5FAA

P356

Q35551712-974F0D53-7ECF-47AE-843C-B5A2AB9E7CF1

P433

Q35551712-4A57F1DF-C828-4FE5-853D-618E6B62DC19

P478

Q35551712-20F152A8-3785-4D6A-A585-7484DD56B283

P50

Q35551712-46073B6E-B98D-4F77-85E6-87EF4A5AD9BA

Q35551712-9682B213-761D-45E8-A23E-7B8CAE24F304

P577

Q35551712-4DDE07B8-42D0-43DF-ABE3-5EE8A4A30EB6

P698

Q35551712-AA488F95-C666-4182-9DC9-B957B1DD2558

P921

Q35551712-2FE78896-EE0A-4052-ACFA-30191F4AE3F2

P932

Q35551712-FDA49ADB-8973-4BEC-8FA8-E5AEE68277F4

P356

MBC.E11-03-0216

P1433

Molecular Biology of the Cell

P1476

p31(comet) acts to ensure time ...... uent to kinetochore attachment

@en

P2093

Håkon Kirkeby Buch

http://www.w3.org/2001/XMLSchema#string

Jagesh V Shah

http://www.w3.org/2001/XMLSchema#string

Michael S Manak

http://www.w3.org/2001/XMLSchema#string

Michelle G Meier

http://www.w3.org/2001/XMLSchema#string

Robert S Hagan

http://www.w3.org/2001/XMLSchema#string

P2860

The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint

p31comet blocks Mad2 activation through structural mimicry

Determinants of conformational dimerization of Mad2 and its inhibition by p31comet

Identification of a MAD2-binding protein, CMT2, and its role in mitosis.

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit

Identification of a physiological E2 module for the human anaphase-promoting complex

Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores

Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells

P304

4236-4246

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1091/MBC.E11-03-0216

http://www.w3.org/2001/XMLSchema#string

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

22

http://www.w3.org/2001/XMLSchema#string

P50

Peter K. Sorger

Patrick Meraldi

P577

2011-09-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

21965286

http://www.w3.org/2001/XMLSchema#string

P921

P932

3216650

http://www.w3.org/2001/XMLSchema#string