Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification
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The biological function of type I receptors of bone morphogenetic protein in boneDevelopment of the Synarcual in the Elephant Sharks (Holocephali; Chondrichthyes): Implications for Vertebral Formation and FusionSurgical Excision of Heterotopic Ossification Leads to Re-Emergence of Mesenchymal Stem Cell Populations Responsible for Recurrence.Targeting of ALK2, a Receptor for Bone Morphogenetic Proteins, Using the Cre/lox System to Enhance Osseous Regeneration by Adipose-Derived Stem Cells.Effects of aging on osteogenic response and heterotopic ossification following burn injury in mice.Treatment of heterotopic ossification through remote ATP hydrolysis.BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints.The immunological contribution to heterotopic ossification disorders.Neofunction of ACVR1 in fibrodysplasia ossificans progressiva.Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders.Granting immunity to FOP and catching heterotopic ossification in the Act.High-throughput screening for modulators of ACVR1 transcription: discovery of potential therapeutics for fibrodysplasia ossificans progressiva.The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signalingNotch signaling pathway promotes osteogenic differentiation of mesenchymal stem cells by enhancing BMP9/Smad signaling.Osteoblast Differentiation and Bone Matrix Formation In Vivo and In Vitro.TGF-β Family Signaling in Connective Tissue and Skeletal Diseases.Conserved signaling pathways underlying heterotopic ossification.Application of human induced pluripotent stem cells to model fibrodysplasia ossificans progressiva.Effectiveness and mode of action of a combination therapy for heterotopic ossification with a retinoid agonist and an anti-inflammatory agent.Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification.Cellular Hypoxia Promotes Heterotopic Ossification by Amplifying BMP Signaling.New Protocol to Optimize iPS Cells for Genome Analysis of Fibrodysplasia Ossificans Progressiva.Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) MutationDirect Mouse Trauma/Burn Model of Heterotopic Ossification.BMP-7 accelerates the differentiation of rabbit mesenchymal stem cells into cartilage through the Wnt/β-catenin pathway.MicroRNA-365 regulates IL-1β-induced catabolic factor expression by targeting HIF-2α in primary chondrocytes.Variable signaling activity by FOP ACVR1 mutations.Depletion of Mast Cells and Macrophages Impairs Heterotopic Ossification in an Acvr1R206H Mouse Model of Fibrodysplasia Ossificans Progressiva.Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva.Animal models of fibrodysplasia ossificans progressiva.Stem cells and heterotopic ossification: Lessons from animal models.A Zebrafish Model of Human Fibrodysplasia Ossificans Progressiva.The Horizon of a Therapy for Rare Genetic Diseases: A "Druggable" Future for Fibrodysplasia Ossificans Progressiva.Multi-system involvement in a severe variant of fibrodysplasia ossificans progressiva (ACVR1 c.772G>A; R258G): A report of two patients.ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A.miR-208a-3p Suppresses Osteoblast Differentiation and Inhibits Bone Formation by Targeting ACVR1.
P2860
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P2860
Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Alk2 regulates early chondroge ...... opic endochondral ossification
@ast
Alk2 regulates early chondroge ...... opic endochondral ossification
@en
type
label
Alk2 regulates early chondroge ...... opic endochondral ossification
@ast
Alk2 regulates early chondroge ...... opic endochondral ossification
@en
prefLabel
Alk2 regulates early chondroge ...... opic endochondral ossification
@ast
Alk2 regulates early chondroge ...... opic endochondral ossification
@en
P2093
P2860
P356
P1433
P1476
Alk2 regulates early chondroge ...... opic endochondral ossification
@en
P2093
Andria L Culbert
Eileen M Shore
Frederick S Kaplan
Salin A Chakkalakal
Tracy A Brennan
P2860
P304
P356
10.1002/STEM.1633
P577
2014-05-01T00:00:00Z