Tyrosine kinases and tyrosine-based activation motifs. Current research on activation via the T cell antigen receptor.
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ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinityp56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulationAnalysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonanceDual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptorThe T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p56lckBinding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteinsRole of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signalingDifferent roles for the Fc epsilon RI gamma chain as a function of the receptor contextActivation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytesInteraction of p72syk with the gamma and beta subunits of the high-affinity receptor for immunoglobulin E, Fc epsilon RITemporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagementTyrosine phosphorylation and association of Syk with Fc gamma RII in monocytic THP-1 cellsRequirement of the SH3 and SH2 domains for the inhibitory function of tyrosine protein kinase p50csk in T lymphocytes.Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells.The unique amino-terminal domain of p56lck regulates interactions with tyrosine protein phosphatases in T lymphocytesRapid T-cell receptor-mediated tyrosine phosphorylation of p120, an Fyn/Lck Src homology 3 domain-binding protein.Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells.CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line.Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2Determinants of the phagocytic signal mediated by the type IIIA Fc gamma receptor, Fc gamma RIIIA: sequence requirements and interaction with protein-tyrosine kinases.The mouse B cell-specific mb-1 gene encodes an immunoreceptor tyrosine-based activation motif (ITAM) protein that may be evolutionarily conserved in diverse species by purifying selection.Cell-surface-expressed T-cell antigen-receptor zeta chain is associated with the cytoskeleton.Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by Fc epsilon R1 cross-linking.B-cell antigen-receptor signalling in lymphocyte development.Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains.PAG-associated FynT regulates calcium signaling and promotes anergy in T lymphocytes.T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex.Development and function of T cells in T cell antigen receptor/CD3 zeta knockout mice reconstituted with Fc epsilon RI gamma.Nitric oxide, mitochondrial hyperpolarization, and T cell activation.Multiple features of the p59fyn src homology 4 domain define a motif for immune-receptor tyrosine-based activation motif (ITAM) binding and for plasma membrane localizationZAP-70 association with T cell receptor zeta (TCRzeta): fluorescence imaging of dynamic changes upon cellular stimulationDifferential effects of zeta and eta transgenes on early alpha/beta T cell development.CD28 signals through acidic sphingomyelinase.Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosisSelective activation of the calcium signaling pathway by altered peptide ligandsReconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene.Role of the multiple T cell receptor (TCR)-zeta chain signaling motifs in selection of the T cell repertoire.Regulation of ZAP-70 intracellular localization: visualization with the green fluorescent protein.7,12-Dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-gamma 1, formation of inositol 1,4,5-trisphosphate, and mobilization of intracel
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Tyrosine kinases and tyrosine-based activation motifs. Current research on activation via the T cell antigen receptor.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Tyrosine kinases and tyrosine- ...... a the T cell antigen receptor.
@ast
Tyrosine kinases and tyrosine- ...... a the T cell antigen receptor.
@en
type
label
Tyrosine kinases and tyrosine- ...... a the T cell antigen receptor.
@ast
Tyrosine kinases and tyrosine- ...... a the T cell antigen receptor.
@en
prefLabel
Tyrosine kinases and tyrosine- ...... a the T cell antigen receptor.
@ast
Tyrosine kinases and tyrosine- ...... a the T cell antigen receptor.
@en
P1476
Tyrosine kinases and tyrosine- ...... ia the T cell antigen receptor
@en
P2093
Klausner RD
Samelson LE
P304
24913-24916
P407
P577
1992-12-01T00:00:00Z