Skp2 is required for incretin hormone-mediated β-cell proliferation
about
Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumorsReport from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell ReplacementHuman β-cell proliferation and intracellular signaling: part 3Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptorsThe negative cell cycle regulators, p27(Kip1), p18(Ink4c), and GSK-3, play critical role in maintaining quiescence of adult human pancreatic β-cells and restrict their ability to proliferate.Repurposing cAMP-modulating medications to promote β-cell replication.Increasing β-cell mass requires additional stimulation for adaptation to secretory demandExpression of Skp2 and p27(kip1) proteins in hypopharyngeal squamous cell carcinoma and its clinical significanceIncretin action in the pancreas: potential promise, possible perils, and pathological pitfalls.LXR activation causes G1/S arrest through inhibiting SKP2 expression in MIN6 pancreatic beta cells.Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.Incretin Therapies Do Not Expand β-Cell Mass or Alter Pancreatic Histology in Young Male Mice.
P2860
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P2860
Skp2 is required for incretin hormone-mediated β-cell proliferation
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Skp2 is required for incretin hormone-mediated β-cell proliferation
@ast
Skp2 is required for incretin hormone-mediated β-cell proliferation
@en
type
label
Skp2 is required for incretin hormone-mediated β-cell proliferation
@ast
Skp2 is required for incretin hormone-mediated β-cell proliferation
@en
prefLabel
Skp2 is required for incretin hormone-mediated β-cell proliferation
@ast
Skp2 is required for incretin hormone-mediated β-cell proliferation
@en
P2093
P2860
P356
P1476
Skp2 is required for incretin hormone-mediated β-cell proliferation
@en
P2093
Anil Bhushan
Sangeeta Dhawan
Shuen-Ing Tschen
P2860
P304
P356
10.1210/ME.2011-1119
P577
2011-10-06T00:00:00Z