Therapeutic potential of AZD1480 for the treatment of human glioblastoma
about
NF-κB and STAT3 in glioblastoma: therapeutic targets coming of ageAZD1480 blocks growth and tumorigenesis of RET- activated thyroid cancer cell linesTherapeutic modulators of STAT signalling for human diseasesThe Jak2 small molecule inhibitor, G6, reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo.PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation.Initial solid tumor testing (stage 1) of AZD1480, an inhibitor of Janus kinases 1 and 2 by the pediatric preclinical testing program.Dynamic analysis of GH receptor conformational changes by split luciferase complementation.α-type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: a phase I clinical trial.Histone H3 phosphorylation in GBM: a new rational to guide the use of kinase inhibitors in anti-GBM therapy.JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth.Nuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomasTyrosine receptor kinase B is a drug target in astrocytomas.Loss of tumor suppressive microRNA-31 enhances TRADD/NF-κB signaling in glioblastomaComplexity of molecular alterations impacts pancreatic cancer prognosis.Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancyActivation of the NF-κB pathway by the STAT3 inhibitor JSI-124 in human glioblastoma cells.Modulating antiangiogenic resistance by inhibiting the signal transducer and activator of transcription 3 pathway in glioblastomaPreferential expression of functional IL-17R in glioma stem cells: potential role in self-renewal.Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivoJAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitorsLoss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma.NF-κB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastomaThe Janus kinases inhibitor AZD1480 attenuates growth of small cell lung cancers in vitro and in vivo.Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma.Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.STAT3/NF-κB-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer.JAK2 inhibition for the treatment of hematologic and solid malignancies.Interleukins in glioblastoma pathophysiology: implications for therapy.Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.Oncogene and non-oncogene addiction in inflammation-associated cancers.Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application.Selective JAK inhibitors.Antiangiogenic therapies for glioblastoma.d,l-Sulforaphane Induces ROS-Dependent Apoptosis in Human Gliomablastoma Cells by Inactivating STAT3 Signaling Pathway.Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma.Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.DawnRank: discovering personalized driver genes in cancer.IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression.Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis.
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P2860
Therapeutic potential of AZD1480 for the treatment of human glioblastoma
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Therapeutic potential of AZD1480 for the treatment of human glioblastoma
@ast
Therapeutic potential of AZD1480 for the treatment of human glioblastoma
@en
type
label
Therapeutic potential of AZD1480 for the treatment of human glioblastoma
@ast
Therapeutic potential of AZD1480 for the treatment of human glioblastoma
@en
prefLabel
Therapeutic potential of AZD1480 for the treatment of human glioblastoma
@ast
Therapeutic potential of AZD1480 for the treatment of human glioblastoma
@en
P2093
P2860
P1476
Therapeutic potential of AZD1480 for the treatment of human glioblastoma
@en
P2093
Catherine P Langford
Dennis Huszar
Etty N Benveniste
G Yancey Gillespie
Jing-Yuan Ma
Susan E Nozell
Ying Zheng
P2860
P304
P356
10.1158/1535-7163.MCT-11-0480
P577
2011-10-25T00:00:00Z