Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics.
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Gephyrin, the enigmatic organizer at GABAergic synapsesThe benzodiazepine binding site of GABA A receptors as a target for the development of novel anxiolyticsGABA A receptors: subtypes provide diversity of function and pharmacologyInternational Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. UpdateGlyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxalPWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in ratsForebrain and midbrain distribution of major benzodiazepine-sensitive GABAA receptor subunits in the adult C57 mouse as assessed with in situ hybridizationSelective labelling of diazepam-insensitive GABAA receptors in vivo using [3H]Ro 15-4513Maternal programming of defensive responses through sustained effects on gene expressionMolecular targets for antiepileptic drug developmentGABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.Neonatal local noxious insult affects gene expression in the spinal dorsal horn of adult ratsA Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor ModelPharmacological profiling of zebrafish behavior using chemical and genetic classification of sleep-wake modifiers.Negative modulation of α₅ GABAA receptors in rats may partially prevent memory impairment induced by MK-801, but not amphetamine- or MK-801-elicited hyperlocomotionTonic GABAA Receptors as Potential Target for the Treatment of Temporal Lobe Epilepsy.Neurosteroids: endogenous regulators of the GABA(A) receptorMutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibitionFunctional role of GABAergic innervation of the cochlea: phenotypic analysis of mice lacking GABA(A) receptor subunits alpha 1, alpha 2, alpha 5, alpha 6, beta 2, beta 3, or delta.Fragrant dioxane derivatives identify beta1-subunit-containing GABAA receptorsIngestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerveHypothalamic regulation of sleep and circadian rhythmsAltered pharmacology and GABA-A receptor subunit expression in dorsal midline thalamic neurons in limbic epilepsyAcute anxiogenic-like effects of selective serotonin reuptake inhibitors are attenuated by the benzodiazepine diazepam in BALB/c mice.The clinical implications of mouse models of enhanced anxiety.Effects of eszopiclone and zolpidem on sleep-wake behavior, anxiety-like behavior and contextual memory in ratsStudying Cerebellar Circuits by Remote Control of Selected Neuronal Types with GABA(A) ReceptorsA gain in GABAA receptor synaptic strength in thalamus reduces oscillatory activity and absence seizures.Hearing loss prevents the maturation of GABAergic transmission in the auditory cortexAmygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice.An anxiety-like phenotype in mice selectively bred for aggression.Endogenous positive allosteric modulation of GABA(A) receptors by diazepam binding inhibitorPositive allosteric modulation of TRPV1 as a novel analgesic mechanism.Pharmacological Properties of DOV 315,090, an ocinaplon metabolite.Reduced brain GABA in primary insomnia: preliminary data from 4T proton magnetic resonance spectroscopy (1H-MRS).Neurosteroids promote phosphorylation and membrane insertion of extrasynaptic GABAA receptors.Sniffer patch laser uncaging response (SPLURgE): an assay of regional differences in allosteric receptor modulation and neurotransmitter clearanceExpression of GABAergic receptors in mouse taste receptor cellsFyn kinase contributes to tyrosine phosphorylation of the GABA(A) receptor gamma2 subunitEnhancement of inhibitory neurotransmission by GABAA receptors having α2,3-subunits ameliorates behavioral deficits in a mouse model of autism
P2860
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P2860
Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Analysis of GABAA receptor fun ...... hetics through mouse genetics.
@ast
Analysis of GABAA receptor fun ...... hetics through mouse genetics.
@en
type
label
Analysis of GABAA receptor fun ...... hetics through mouse genetics.
@ast
Analysis of GABAA receptor fun ...... hetics through mouse genetics.
@en
prefLabel
Analysis of GABAA receptor fun ...... hetics through mouse genetics.
@ast
Analysis of GABAA receptor fun ...... hetics through mouse genetics.
@en
P1476
Analysis of GABAA receptor fun ...... hetics through mouse genetics.
@en
P2093
Hanns Möhler
Uwe Rudolph
P304
P356
10.1146/ANNUREV.PHARMTOX.44.101802.121429
P577
2004-01-01T00:00:00Z