PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. - Wikidata - awgldk - TriplyDB

PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.

PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.

http://www.wikidata.org/entity/Q35661819

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The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex Tumor suppressor SMAR1 mediates cyclin D1 repression by recruitment of the SIN3/histone deacetylase 1 complex Tumours with PI3K activation are resistant to dietary restriction Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1 Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice.MicroRNAs MiR-17, MiR-20a, and MiR-106b act in concert to modulate E2F activity on cell cycle arrest during neuronal lineage differentiation of USSC.beta1-Integrin-collagen interaction suppresses FoxO3a by the coordination of Akt and PP2A Invasive glioblastoma cells acquire stemness and increased Akt activation.Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex.PTEN loss accelerates KrasG12D-induced pancreatic cancer development Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.Indole-3-carbinol prevents PTEN loss in cervical cancer in vivo Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice.Cyclin D1 promotes anchorage-independent cell survival by inhibiting FOXO-mediated anoikis.Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway Gene expression analysis of PTEN positive glioblastoma stem cells identifies DUB3 and Wee1 modulation in a cell differentiation model PTEN reconstitution alters glioma responses to c-Met pathway inhibition.Phosphatase and tensin homolog on chromosome 10 is phosphorylated in primary effusion lymphoma and Kaposi's sarcoma.HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells NDR functions as a physiological YAP1 kinase in the intestinal epithelium.The different roles of cyclinD1-CDK4 in STP and mGluR-LTD during the postnatal development in mice hippocampus area CA1.Synergistic apoptosis of MCF-7 breast cancer cells by 2-methoxyestradiol and bis(ethyl)norspermine Phosphatidylinositol 3-kinase/Akt signaling enhances nuclear localization and transcriptional activity of BRCA1 The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1α Phosphorylation.Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma Pocket protein function in melanocyte homeostasis and neoplasia.Deficiency in metabolic regulators PPARγ and PTEN cooperates to drive keratinizing squamous metaplasia in novel models of human tissue regeneration.AKT expression is associated with degree of pathologic response in adenocarcinoma of the esophagus treated with neoadjuvant therapy.PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex.Retinoblastoma and phosphate and tensin homolog tumor suppressors: impact on ductal carcinoma in situ progression PTEN, more than the AKT pathway.Microarray-Based Phospho-Proteomic Profiling of Complex Biological Systems.TBX2 represses PTEN in rhabdomyosarcoma and skeletal muscle.NHERF1/EBP50 Suppresses Wnt-β-Catenin Pathway-Driven Intestinal Neoplasia.Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells.

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P2860

PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.

http://www.wikidata.org/entity/Q35661819

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

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name

PTEN induces cell cycle arrest ...... ear localization of cyclin D1.

@ast

PTEN induces cell cycle arrest ...... ear localization of cyclin D1.

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type

label

PTEN induces cell cycle arrest ...... ear localization of cyclin D1.

@ast

PTEN induces cell cycle arrest ...... ear localization of cyclin D1.

@en

prefLabel

PTEN induces cell cycle arrest ...... ear localization of cyclin D1.

@ast

PTEN induces cell cycle arrest ...... ear localization of cyclin D1.

@en

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MCB.23.17.6139-6149.2003

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Molecular and Cellular Biology

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PTEN induces cell cycle arrest ...... ear localization of cyclin D1.

@en

P2093

Aurelian Radu

http://www.w3.org/2001/XMLSchema#string

Hidesaburo Hanafusa

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Maria-Magdalena Georgescu

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Tsuyoshi Akagi

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Valerie Neubauer

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P2860

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Direct control of the Forkhead transcription factor AFX by protein kinase B

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

A genetic model for colorectal tumorigenesis

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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10.1128/MCB.23.17.6139-6149.2003

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180959

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