The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo.
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Sequential pathogenesis of metastatic VHL mutant clear cell renal cell carcinoma: putting it together with a translational perspectiveHypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP)Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growthHypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasionHypoxia-inducible factors have distinct and stage-specific roles during reprogramming of human cells to pluripotency.The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype.Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter.Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression.Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic conditionNon-canonical HIF-2α function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop.Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter constructKaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cellsSuppression of glioma progression by Egln3Interdependence of HIF-1α and TGF-β/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression.Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.The contributions of HIF-target genes to tumor growth in RCC.HIF induces human embryonic stem cell markers in cancer cells.PTEN induces apoptosis and cavitation via HIF-2-dependent Bnip3 upregulation during epithelial lumen formationGenetic and functional studies implicate HIF1α as a 14q kidney cancer suppressor geneHypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism.Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1α.Duodenal cytochrome b (DCYTB) in iron metabolism: an update on function and regulation.Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL.Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer.Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eyeHIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition.Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis.Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo.Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells.The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma.EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.The VHL/HIF axis in clear cell renal carcinoma.Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in miceStabilization of HIF-1alpha is critical to improve wound healing in diabetic mice.Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functionsBiology of hypoxia-inducible factor-2alpha in development and diseaseGenetic causes of erythrocytosis and the oxygen-sensing pathway.A general map of iron metabolism and tissue-specific subnetworks.
P2860
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P2860
The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The hypoxia-inducible factor 2 ...... e renal tumorigenesis in vivo.
@ast
The hypoxia-inducible factor 2 ...... e renal tumorigenesis in vivo.
@en
type
label
The hypoxia-inducible factor 2 ...... e renal tumorigenesis in vivo.
@ast
The hypoxia-inducible factor 2 ...... e renal tumorigenesis in vivo.
@en
prefLabel
The hypoxia-inducible factor 2 ...... e renal tumorigenesis in vivo.
@ast
The hypoxia-inducible factor 2 ...... e renal tumorigenesis in vivo.
@en
P2093
P2860
P356
P1476
The hypoxia-inducible factor 2 ...... e renal tumorigenesis in vivo.
@en
P2093
P2860
P304
P356
10.1128/MCB.01514-06
P407
P577
2007-01-12T00:00:00Z