Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes - Wikidata - awgldk - TriplyDB

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

http://www.wikidata.org/entity/Q35794263

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Nutrition and the risk of Alzheimer's disease Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment Insulin: an emerging treatment for Alzheimer's disease dementia?The impairment of insulin signaling in Alzheimer's disease Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's disease Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome Food for thought: the role of appetitive peptides in age-related cognitive decline Brain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogs Roles of vascular and metabolic components in cognitive dysfunction of Alzheimer disease: short- and long-term modification by non-genetic risk factors Aberrant insulin signaling in Alzheimer's disease: current knowledge Insulin in the nervous system and the mind: Functions in metabolism, memory, and mood β-Hydroxy-β-Methylbutyrate (HMB) Promotes Neurite Outgrowth in Neuro2a Cells Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation Diabetes alters KIF1A and KIF5B motor proteins in the hippocampus Mechanisms underlying insulin deficiency-induced acceleration of β-amyloidosis in a mouse model of Alzheimer's disease Neuroadrenergic dysfunction along the diabetes continuum: a comparative study in obese metabolic syndrome subjects.Intracerebroventricular streptozotocin exacerbates Alzheimer-like changes of 3xTg-AD mice Early life nutrient restriction impairs blood-brain metabolic profile and neurobehavior predisposing to Alzheimer's disease with aging.Brain gene expression of a sporadic (icv-STZ Mouse) and a familial mouse model (3xTg-AD mouse) of Alzheimer's disease.The nature, significance, and glucagon-like peptide-1 analog treatment of brain insulin resistance in Alzheimer's disease.Folic Acid Reduces Tau Phosphorylation by Regulating PP2A Methylation in Streptozotocin-Induced Diabetic Mice.Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi.LDL phenotype in subjects with mild cognitive impairment and Alzheimer's disease.The meteorology of cytokine storms, and the clinical usefulness of this knowledge Insulin Attenuates Beta-Amyloid-Associated Insulin/Akt/EAAT Signaling Perturbations in Human Astrocytes Tissue-specific insulin signaling in the regulation of metabolism and aging.Global analysis of S-nitrosylation sites in the wild type (APP) transgenic mouse brain-clues for synaptic pathology.Tau phosphorylation and μ-calpain activation mediate the dexamethasone-induced inhibition on the insulin-stimulated Akt phosphorylation.Age-dependent modulation of synaptic plasticity and insulin mimetic effect of lipoic acid on a mouse model of Alzheimer's disease.Insulin resistance and gray matter volume in neurodegenerative disease.Deficient hippocampal insulin signaling and augmented Tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in Zucker rats.Reverse differentiation as a gene filtering tool in genome expression profiling of adipogenesis for fat marker gene selection and their analysis.Characterization of cognitive deficits in spontaneously hypertensive rats, accompanied by brain insulin receptor dysfunction.Amyloid-β oligomers induce differential gene expression in adult human brain slices.Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.Unaltered Prion Pathogenesis in a Mouse Model of High-Fat Diet-Induced Insulin Resistance.Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease.Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain.

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P2860

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

http://www.wikidata.org/entity/Q35794263

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

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Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

@en

type

label

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

@ast

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

@en

prefLabel

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

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Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

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The Journal of Pathology

P1476

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

@en

P2093

Fei Liu

http://www.w3.org/2001/XMLSchema#string

Khalid Iqbal

http://www.w3.org/2001/XMLSchema#string

Ying Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain

Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

Insulin signaling, diabetes mellitus and risk of Alzheimer disease.

Mechanisms of tau-induced neurodegeneration.

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

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54-62

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10.1002/PATH.2912

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1

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225

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Inge Grundke-Iqbal

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2011-05-19T00:00:00Z

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51152062

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21598254

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Alzheimer's disease

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4484598

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