Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy
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Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulationTransient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathwaysA-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in α1-adrenergic receptor-induced p38 activationA-kinase-anchoring protein-Lbc anchors IκB kinase β to support interleukin-6-mediated cardiomyocyte hypertrophyTargeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophyInhibition of norepinephrine-induced cardiac hypertrophy in s100beta transgenic mice.Decreased blood pressure response in mice deficient of the alpha1b-adrenergic receptorThe alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouseAkt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletionThe A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophyDual role for glucocorticoids in cardiomyocyte hypertrophy and apoptosisEmbryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice.Serotonin 2B receptor is required for heart developmentThe zinc finger-only protein Zfp260 is a novel cardiac regulator and a nuclear effector of alpha1-adrenergic signaling.Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassayPressure load: the main factor for altered gene expression in right ventricular hypertrophy in chronic hypoxic rats.Evolution and pathophysiology of chronic systolic heart failure.Long-term α1B-adrenergic receptor activation shortens lifespan, while α1A-adrenergic receptor stimulation prolongs lifespan in association with decreased cancer incidence.Role of the sympathetic nervous system in cardiac remodeling in hypertension.Cardiac hypertrophy and failure: lessons learned from genetically engineered mice.Adrenergic regulation of cardiac myocyte apoptosis.The α1-adrenergic receptors: diversity of signaling networks and regulationCardiac 7-transmembrane-spanning domain receptor portfolios: diversify, diversify, diversify.Position independent expression and developmental regulation is directed by the beta myosin heavy chain gene's 5' upstream region in transgenic mice.The alpha(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction.Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytesAlpha-1-adrenergic receptors: targets for agonist drugs to treat heart failure.Alpha1a-adrenoceptor genetic variant induces cardiomyoblast-to-fibroblast-like cell transition via distinct signaling pathways.The alpha1b-adrenergic receptor subtype: molecular properties and physiological implications.Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardiumThe eukaryotic translation initiation factor 3f (eIF3f) interacts physically with the alpha 1B-adrenergic receptor and stimulates adrenoceptor activity.Gain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice.Ligand-induced overexpression of a constitutively active beta2-adrenergic receptor: pharmacological creation of a phenotype in transgenic mice.Inhibitory control of synaptic and behavioral plasticity by octopaminergic signaling.Overexpression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block.Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure.Transgenic Galphaq overexpression induces cardiac contractile failure in miceProgressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.Challenges and opportunities in dystrophin-deficient cardiomyopathy gene therapy.α₁A-adrenergic receptors regulate cardiac hypertrophy in vivo through interleukin-6 secretion.
P2860
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P2860
Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Myocardial expression of a con ...... ce induces cardiac hypertrophy
@ast
Myocardial expression of a con ...... ce induces cardiac hypertrophy
@en
type
label
Myocardial expression of a con ...... ce induces cardiac hypertrophy
@ast
Myocardial expression of a con ...... ce induces cardiac hypertrophy
@en
prefLabel
Myocardial expression of a con ...... ce induces cardiac hypertrophy
@ast
Myocardial expression of a con ...... ce induces cardiac hypertrophy
@en
P2093
P2860
P356
P1476
Myocardial expression of a con ...... ce induces cardiac hypertrophy
@en
P2093
C A Milano
H A Rockman
M E Venable
P C Dolber
R J Lefkowitz
P2860
P304
10109-10113
P356
10.1073/PNAS.91.21.10109
P407
P577
1994-10-01T00:00:00Z