Mutations and altered expression of p16INK4 in human cancer. - Wikidata - awgldk - TriplyDB

Mutations and altered expression of p16INK4 in human cancer.

Mutations and altered expression of p16INK4 in human cancer.

http://www.wikidata.org/entity/Q35892778

about

WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4 Growth suppression by p16ink4 requires functional retinoblastoma protein Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6 Effect of 5-azacytidine and galectin-1 on growth and differentiation of the human b lymphoma cell line bl36 The Role of microRNAs in the Diagnosis and Treatment of Pancreatic Adenocarcinoma Clinicopathological Significance and Potential Drug Target of CDKN2A/p16 in Endometrial Carcinoma Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells Biochemical characterization of p16INK4- and p18-containing complexes in human cell lines A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma No p16INK4A/CDKN2/MTS1 mutations independent of p53 status in soft tissue sarcomas.Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information.Failure of cell cleavage induces senescence in tetraploid primary cells.Contributions of differential p53 expression in the spontaneous immortalization of a chicken embryo fibroblast cell line.Insights into cancer from transgenic mouse models.Pancreatic adenocarcinoma: epidemiology and genetics.Genetic replacement of cyclin D1 function in mouse development by cyclin D2.DNA methylation changes and multiple myeloma.Modeling human lung cancer in mice: similarities and shortcomings.Circadian variation in expression of G1 phase cyclins D1 and E and cyclin-dependent kinase inhibitors p16 and p21 in human bowel mucosa Aberrant cytological localization of p16 and CDK4 in colorectal epithelia in the normal adenoma carcinoma sequence.The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.CpG methylation is maintained in human cancer cells lacking DNMT1.UV irradiation augments lymphoid malignancies in mice with one functional copy of wild-type p53.Mechanism targeted discovery of antitumor marine natural products.Diagnostic and prognostic tumor markers in the gastrointestinal tract.HTLV-I Tax related dysfunction of cell cycle regulators and oncogenesis of adult T cell leukemia.What we could do now: molecular pathology of colorectal cancer.Ladder-like amplification of the type I interferon gene cluster in the human osteosarcoma cell line MG63 Methylation and colorectal cancer.Alterations of P16 (MTS1) in node-positive non-small cell lung carcinomas.The specificity and patterns of staining in human cells and tissues of p16INK4a antibodies demonstrate variant antigen binding.Long-term quiescent fibroblast cells transit into senescence P16 gene hypermethylation and hepatocellular carcinoma: a systematic review and meta-analysis.Expression patterns of cyclin D1 and related proteins regulating G1-S phase transition in uveal melanoma and retinoblastoma.Association between P16INK4a promoter methylation and HNSCC: a meta-analysis of 21 published studies.Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer.Correlation of clinicopathological features with immunohistochemical expression of cell cycle regulatory proteins p16 and retinoblastoma: distinct association with keratinisation and differentiation in oral cavity squamous cell carcinoma.Genetic evidence in melanoma and bladder cancers that p16 and p53 function in separate pathways of tumor suppression

P2860

Q24305671-2B6612FE-3AA4-4871-9F08-B1B53A1B4E19 Q24314643-43A21289-184F-45DC-B86A-B09ACFDF91A8 Q24317567-A23C1972-ED29-430B-86E3-16E5091096B4 Q24650807-03282697-843B-46CD-8208-BBCF84793666 Q24652510-239023C1-AE51-4504-9058-4C0F50B34D25 Q24805197-34EA7602-5BBE-451E-BD32-E78391EDBEE8 Q26744298-28975FCB-D8A3-4D72-953B-9247C5B6089C Q26797456-C9F7075B-7EB1-4056-8E04-7EAC8B33D731 Q28118300-AAFE62DD-CF93-4C78-9FDF-3DD0FF537978 Q28281959-E8C44973-1F62-4E37-B30A-A2E96834AAAE Q28296086-973FD240-9B39-470B-81A3-E854215243D5 Q30321283-891EC1A0-C794-4627-BF47-C715759D143C Q30322978-C7CAF6FB-A48B-481F-8741-56955E43C10B Q30592232-72CCC46E-D16C-4159-AD38-F3C883D42B19 Q33248487-235D78E0-F348-4DA0-BCEA-5240E60115E3 Q33643327-896914FA-73FE-4929-8343-BD05C3EA9834 Q33677968-F34CC98E-8C92-40A6-8D63-115E999F5053 Q33714058-FFE153A0-4001-4451-BE84-D797272008B3 Q33735188-4B15A016-839A-4DC3-9C06-1A2376A22EB1 Q33739273-79BE6897-2C45-460B-A841-159ADD01BB76 Q33867338-9213868E-B544-473D-94B9-E97E02F517A9 Q33869183-B3358324-8BEC-4FC9-8D71-69F102B7BF10 Q33889383-55B6CB22-5C15-496F-A0F9-FA08AEE62523 Q33901029-E2A564BC-79C9-4C2C-BBA6-46515852D822 Q33933792-6EF5FBB6-33CF-433F-8F9A-29C4C6A6D194 Q34012630-762589E6-9B28-4453-A9D3-C6BFC8FE6794 Q34277292-17C98591-98D2-4D71-9F6D-AEF544D23A13 Q34293483-0274040F-4DBD-4979-9047-3EB60FDBE82F Q34321746-BDDA65C0-3D10-4B27-BD83-37AA3596F599 Q34344422-F37355F9-5CE8-4A4C-87CE-E6EED5403AF7 Q34378429-7342E1FA-E25B-4DDD-94A2-85665F4E0F39 Q34423364-482AAF3A-EA75-459C-8793-329AEA9F1C54 Q34544920-158A34E9-3482-4BEA-9448-1185C8E981E3 Q34757728-C1C9A702-5C26-4568-92BA-EA02F01083D2 Q35093637-5A05B4AE-819A-4A49-A8F8-5D2E26EC225A Q35306247-6A4F1AB9-3F45-497B-9F9E-026B35836BB1 Q35593076-CCD143EE-5AFD-4CB1-9B47-E60D2A22DA56 Q35735278-67215BCD-088E-490F-B554-7E2D36DCAEAE Q35770139-AED40430-63F8-45BC-BF44-A2F64B58BF87 Q35795085-4F7B2274-33FD-481A-82C5-1BCC2861DA57

P2860

Mutations and altered expression of p16INK4 in human cancer.

http://www.wikidata.org/entity/Q35892778

description

1994 nî lūn-bûn

@nan

1994年の論文

@ja

1994年論文

@yue

1994年論文

@zh-hant

1994年論文

@zh-hk

1994年論文

@zh-mo

1994年論文

@zh-tw

1994年论文

@wuu

1994年论文

@zh

1994年论文

@zh-cn

name

Mutations and altered expression of p16INK4 in human cancer.

@ast

Mutations and altered expression of p16INK4 in human cancer.

@en

type

label

Mutations and altered expression of p16INK4 in human cancer.

@ast

Mutations and altered expression of p16INK4 in human cancer.

@en

prefLabel

Mutations and altered expression of p16INK4 in human cancer.

@ast

Mutations and altered expression of p16INK4 in human cancer.

@en

P1433

Q35892778-ACD9ADE2-B54E-4B10-8E13-7C007A8F2DAE

P1476

Q35892778-456CD081-6E9A-486F-A08A-0943AE83A4F3

P2093

Q35892778-0FC43A29-4493-4933-9693-E5B65B891B80

Q35892778-1BC6852F-9A04-493D-915C-FC1AF5F48AA7

Q35892778-298E70F1-AE44-4AEF-9CDF-C3E000BE4992

Q35892778-405D1CDE-EBB7-4CAC-87C5-4CF188945806

Q35892778-46AE0FB7-C936-4D58-B664-C54ECDBF8F3B

Q35892778-8281D734-2AA3-4D27-AF40-3C7ED3733465

Q35892778-B0E9A271-BFD3-4DAD-A514-52D95AB19225

Q35892778-E4A301FD-BD49-4359-BF57-06A34156AD9B

P2860

Q35892778-0D84BE68-E6E2-404E-B7ED-382CB6852FAA

Q35892778-0F1D3F59-6C4B-4203-A829-D29FB418CB27

Q35892778-1C5D65E9-C568-4C20-9520-8589D13F8A79

Q35892778-27F420A1-FF7E-4C4C-A75C-79915AB09B7E

Q35892778-33C07D0A-8694-4C93-9B6B-41B8BDD1E398

Q35892778-3463D98B-AFFE-4E38-9347-0C488C6FD0CA

Q35892778-3E36F374-03A7-4887-99EE-9C8954A8A2D0

Q35892778-3F524828-70CB-4BF7-8D3C-988568CAAB2A

Q35892778-402CFA7A-5FD5-4675-9544-68DFB11EF4EF

Q35892778-4197EA80-D10C-4A99-BBB6-8EA7A22E4114

P304

Q35892778-1FE46209-CF8C-4E58-BFDD-6A2CBAE14CE4

P31

Q35892778-74035F54-A221-4A13-8E04-2EB1891AB288

P356

Q35892778-24F197EF-A7BF-4E0B-8FD5-17D82EE7DA1C

P407

Q35892778-62295EC3-1F9E-4BE6-AD9F-0CA8057B3295

P433

Q35892778-C79494E4-82F6-4199-B8E0-0F09C7765505

P478

Q35892778-7E5AAC53-1FD5-472F-82C0-6D97AC0AC0BC

P50

Q35892778-783F4905-C863-4A8A-8DE1-CC86841511CA

Q35892778-CF3FD2DA-0E8B-461B-B213-009A1E0D36D0

P577

Q35892778-D8B90ED1-ACD8-4F25-87F1-BEDFFFD4E63A

P5875

Q35892778-93924C3E-3D90-4CB1-8D41-3C656885A7A1

P698

Q35892778-06275A90-32D4-4262-97FB-017267B0B490

P932

Q35892778-CD292D63-806A-4260-AB0E-35D9AAA648A9

P356

PNAS.91.23.11045

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Mutations and altered expression of p16INK4 in human cancer

@en

P2093

A Okamoto

http://www.w3.org/2001/XMLSchema#string

B Gerwin

http://www.w3.org/2001/XMLSchema#string

D H Beach

http://www.w3.org/2001/XMLSchema#string

D J Demetrick

http://www.w3.org/2001/XMLSchema#string

E A Spillare

http://www.w3.org/2001/XMLSchema#string

K Forrester

http://www.w3.org/2001/XMLSchema#string

K Hagiwara

http://www.w3.org/2001/XMLSchema#string

W P Bennett

http://www.w3.org/2001/XMLSchema#string

P2860

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

WAF1, a potential mediator of p53 tumor suppression

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

A cell cycle regulator potentially involved in genesis of many tumor types

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

Physical interaction of the retinoblastoma protein with human D cyclins

p53 mutations in human cancers

G1 events and regulation of cell proliferation

P304

11045-11049

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.91.23.11045

http://www.w3.org/2001/XMLSchema#string

P407

P433

23

http://www.w3.org/2001/XMLSchema#string

P478

91

http://www.w3.org/2001/XMLSchema#string

P50

P577

1994-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

235616008

http://www.w3.org/2001/XMLSchema#string

P698

7972006

http://www.w3.org/2001/XMLSchema#string

P932

45163

http://www.w3.org/2001/XMLSchema#string