Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region
about
B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia.Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase.Btk dosage determines sensitivity to B cell antigen receptor cross-linkingAgammaglobulinemia: causative mutations and their implications for novel therapies.BTK Signaling in B Cell Differentiation and Autoimmunity.Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease.Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA.A Btk transgene restores the antiviral TI-2 antibody responses of xid mice in a dose-dependent fashion.Bi-directional regulation between tyrosine kinase Etk/BMX and tumor suppressor p53 in response to DNA damage.Murine MHC class II locus control region drives expression of human beta-glucocerebrosidase in antigen presenting cells of transgenic mice.The effect of glycosylation of antigens on the antibody responses against Echinostoma caproni (Trematoda: Echinostomatidae).
P2860
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P2860
Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Correction of the X-linked imm ...... omplex Ea locus control region
@ast
Correction of the X-linked imm ...... omplex Ea locus control region
@en
type
label
Correction of the X-linked imm ...... omplex Ea locus control region
@ast
Correction of the X-linked imm ...... omplex Ea locus control region
@en
prefLabel
Correction of the X-linked imm ...... omplex Ea locus control region
@ast
Correction of the X-linked imm ...... omplex Ea locus control region
@en
P2093
P2860
P356
P1476
Correction of the X-linked imm ...... omplex Ea locus control region
@en
P2093
Dingjan GM
Grosveld F
Hendriks RW
Savelkoul HF
P2860
P304
P356
10.1073/PNAS.94.2.610
P407
P577
1997-01-01T00:00:00Z