A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication
about
A vertebrate gene, ticrr, is an essential checkpoint and replication regulatorPSF1 is essential for early embryogenesis in miceAncestral paralogs and pseudoparalogs and their role in the emergence of the eukaryotic cellDistinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forksIsolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicaseA requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replicationThe replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplicationHow do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeastDNA replication in the archaeaHuman Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replicationMolecular architecture of the human GINS complex.Tackling an essential problem in functional proteomics of Saccharomyces cerevisiaeDNA binding and helicase actions of mouse MCM4/6/7 helicase.Nuclear distribution and chromatin association of DNA polymerase alpha-primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast.Ring of Change: CDC48/p97 Drives Protein Dynamics at ChromatinArchaeal MCM Proteins as an Analog for the Eukaryotic Mcm2-7 Helicase to Reveal Essential Features of Structure and FunctionLoading and activation of DNA replicative helicases: the key step of initiation of DNA replicationStructure of the human GINS complex and its assembly and functional interface in replication initiationCrystal structure of the human GINS complexCrystal structure of the GINS complex and functional insights into its role in DNA replicationCell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase.Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.A CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11Efficient initiation of DNA replication in eukaryotes requires Dpb11/TopBP1-GINS interactionSld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast.A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome.Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins.Identification of Mcm2 phosphorylation sites by S-phase-regulating kinasesRequirement of SLD5 for early embryogenesisGEMC1 is a TopBP1-interacting protein required for chromosomal DNA replicationThe Dbf4-Cdc7 kinase promotes Mcm2-7 ring opening to allow for single-stranded DNA extrusion and helicase assembly.Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases.De novo assembly of genuine replication forks on an immobilized circular plasmid in Xenopus egg extracts.The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extractsMCM-GINS and MCM-MCM interactions in vivo visualised by bimolecular fluorescence complementation in fission yeastSuppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2Snm1B interacts with PSF2.Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint
P2860
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P2860
A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
A novel ring-like complex of X ...... initiation of DNA replication
@ast
A novel ring-like complex of X ...... initiation of DNA replication
@en
type
label
A novel ring-like complex of X ...... initiation of DNA replication
@ast
A novel ring-like complex of X ...... initiation of DNA replication
@en
prefLabel
A novel ring-like complex of X ...... initiation of DNA replication
@ast
A novel ring-like complex of X ...... initiation of DNA replication
@en
P2093
P2860
P356
P1433
P1476
A novel ring-like complex of X ...... initiation of DNA replication
@en
P2093
Haruhiko Takisawa
Hiroyuki Araki
Toshiaki Arata
Yasunori Komori
Yoichiro Kamimura
Yoshitami Hashimoto
Youhei Takase
Yumiko Kubota
P2860
P304
P356
10.1101/GAD.1070003
P577
2003-05-01T00:00:00Z