siRNA off-target effects in genome-wide screens identify signaling pathway members. - Wikidata - awgldk - TriplyDB

siRNA off-target effects in genome-wide screens identify signaling pathway members.

siRNA off-target effects in genome-wide screens identify signaling pathway members.

http://www.wikidata.org/entity/Q35992666

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A CRISPR CASe for high-throughput silencing High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy Genetic screens and functional genomics using CRISPR/Cas9 technology RNAi screening comes of age: improved techniques and complementary approaches Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis.Screening and functional analysis of the peroxiredoxin specifically expressed in Bursaphelenchus xylophilus--the causative agent of pine wilt disease.Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens.The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase.C911: A bench-level control for sequence specific siRNA off-target effects High-throughput validation of ceRNA regulatory networks Simultaneous analysis of large-scale RNAi screens for pathogen entry.Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens.Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing.High-throughput functional genomics using CRISPR-Cas9.Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects Deciphering Seed Sequence Based Off-Target Effects in a Large-Scale RNAi Reporter Screen for E-Cadherin Expression gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma Outlier analysis of functional genomic profiles enriches for oncology targets and enables precision medicine.TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP).Knocking down the obstacles to functional genomics data sharing.Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.Antiviral Stratagems Against HIV-1 Using RNA Interference (RNAi) Technology.Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines.High-Throughput Small Interfering RNA Screening Identifies Phosphatidylinositol 3-Kinase Class II Alpha as Important for Production of Human Cytomegalovirus Virions Impact of RNA-guided technologies for target identification and deconvolution.Detecting and overcoming systematic bias in high-throughput screening technologies: a comprehensive review of practical issues and methodological solutions.A Perspective on the Future of High-Throughput RNAi Screening: Will CRISPR Cut Out the Competition or Can RNAi Help Guide the Way?Seed-effect modeling improves the consistency of genome-wide loss-of-function screens and identifies synthetic lethal vulnerabilities in cancer cells.Defining a Cancer Dependency Map.Synthetic lethality and cancer.Triad of human cellular proteins, IRF2, FAM111A, and RFC3, restrict replication of orthopoxvirus SPI-1 host-range mutants.Image-based siRNA screen to identify kinases regulating Weibel-Palade body size control using electroporation.Novel SUMO-Protease SENP7S Regulates β-catenin Signaling and Mammary Epithelial Cell Transformation.Evaluation and control of miRNA-like off-target repression for RNA interference.OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung.Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

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siRNA off-target effects in genome-wide screens identify signaling pathway members.

http://www.wikidata.org/entity/Q35992666

description

2012 nî lūn-bûn

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name

siRNA off-target effects in genome-wide screens identify signaling pathway members.

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siRNA off-target effects in genome-wide screens identify signaling pathway members.

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siRNA off-target effects in genome-wide screens identify signaling pathway members.

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siRNA off-target effects in genome-wide screens identify signaling pathway members.

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prefLabel

siRNA off-target effects in genome-wide screens identify signaling pathway members.

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siRNA off-target effects in genome-wide screens identify signaling pathway members.

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Scientific Reports

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siRNA off-target effects in genome-wide screens identify signaling pathway members.

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Amit Bahl

http://www.w3.org/2001/XMLSchema#string

Julja Burchard

http://www.w3.org/2001/XMLSchema#string

Marc Ferrer

http://www.w3.org/2001/XMLSchema#string

Misha Rajaram

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Shane Marine

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LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

Genomic screening with RNAi: results and challenges

KEGG for representation and analysis of molecular networks involving diseases and drugs

A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer

NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs

The UCSC Table Browser data retrieval tool

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