Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease. - Wikidata - awgldk - TriplyDB

Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease.

Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease.

http://www.wikidata.org/entity/Q35993416

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TM6SF2 E167K Variant, a Novel Genetic Susceptibility Variant, Contributing to Nonalcoholic Fatty Liver Disease Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?Pathophysiology of Non Alcoholic Fatty Liver Disease Molecular Pathogenesis of NASH High susceptibility to fatty liver disease in two-pore channel 2-deficient mice The role of signalling in cellular cholesterol homeostasis Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans Multi-SNP analysis of GWAS data identifies pathways associated with nonalcoholic fatty liver disease Treatment of nonalcoholic fatty liver disease: role of AMPK.MicroRNAs in nonalcoholic fatty liver disease: novel biomarkers and prognostic tools during the transition from steatosis to hepatocarcinoma.Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse non-alcoholic steatohepatitis.Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis Non-coding RNAs and lipid metabolism MicroRNA-223 coordinates cholesterol homeostasis Mechanism of the promotion of steatotic HepG2 cell apoptosis by cholesterol Lipoprotein subclass metabolism in nonalcoholic steatohepatitis.Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis.Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis Gallbladder gallstone disease is associated with newly diagnosed coronary artery atherosclerotic disease: a cross-sectional study.Lessons from hepatocyte-specific Cyp51 knockout mice: impaired cholesterol synthesis leads to oval cell-driven liver injury.Potential epigenetic mechanism in non-alcoholic Fatty liver disease Severity of nonalcoholic fatty liver disease and progression to cirrhosis are associated with atherogenic lipoprotein profile.SteatoNet: the first integrated human metabolic model with multi-layered regulation to investigate liver-associated pathologies.AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver.Activation of the GP130-STAT3 axis and its potential implications in nonalcoholic fatty liver disease Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity.Lysosomal Acid Lipase Activity: A Tool for the Detection and Management of Fatty Liver Disease?Crude triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non-alcoholic fatty liver disease model.Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease.Low-Dose Cadmium Causes Metabolic and Genetic Dysregulation Associated With Fatty Liver Disease in Mice.Optimized Rapeseed Oils Rich in Endogenous Micronutrients Protect High Fat Diet Fed Rats from Hepatic Lipid Accumulation and Oxidative Stress Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat Hepatocytes Folic acid supplementation during high-fat diet feeding restores AMPK activation via an AMP-LKB1-dependent mechanism.Sex-Specific Differences in Hepatic Fat Oxidation and Synthesis May Explain the Higher Propensity for NAFLD in Men.Altered regulation of miR-34a and miR-483-3p in alcoholic hepatitis and DDC fed mice.Choline, Its Potential Role in Nonalcoholic Fatty Liver Disease, and the Case for Human and Bacterial Genes Saturated fat and cholesterol are critical to inducing murine metabolic syndrome with robust nonalcoholic steatohepatitis.

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P2860

Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease.

http://www.wikidata.org/entity/Q35993416

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J.CMET.2012.04.004

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Cell Metabolism

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Increased hepatic synthesis an ...... alcoholic fatty liver disease.

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Arun J Sanyal

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Ashwani Kapoor

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Faridoddin Mirshahi

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Hae-Ki Min

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Huiping Zhou

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James Maher

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John Kellum

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P2860

Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liver

The LDL receptor

Molecular biology of PCSK9: its role in LDL metabolism

Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease

Phosphorylation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and modulation of its enzymic activity by calcium-activated and phospholipid-dependent protein kinase

MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis

Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

Molecular mediators of hepatic steatosis and liver injury

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5

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224912766

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22560219

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3361911

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