What keeps us ticking: a funny current, a calcium clock, or both?
about
Mechanisms of Electrical Activation and Conduction in the Gastrointestinal System: Lessons from Cardiac ElectrophysiologyRabbit models of cardiac mechano-electric and mechano-mechanical couplingMechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channelsThe Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialHyperpolarization-activated current, If, in mathematical models of rabbit sinoatrial node pacemaker cellsFibrosis: a structural modulator of sinoatrial node physiology and dysfunctionIon Channels in the HeartFunny channel gene mutations associated with arrhythmiasModern concepts concerning the origin of the heartbeat.A network-oriented perspective on cardiac calcium signalingA Systemized Approach to Investigate Ca(2+) Synchronization in Clusters of Human Induced Pluripotent Stem-Cell Derived CardiomyocytesAdvances in the management of heart failure: the role of ivabradineIonic mechanisms of arrhythmogenesisThe importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeatCardiac ryanodine receptors control heart rate and rhythmicity in adult miceDeep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4Delayed afterdepolarization in intact canine sinoatrial node as a novel mechanism for atrial arrhythmia.Optical mapping of the electrical activity of isolated adult zebrafish hearts: acute effects of temperature.Paradoxical effect of increased diastolic Ca(2+) release and decreased sinoatrial node activity in a mouse model of catecholaminergic polymorphic ventricular tachycardia.How is the heart rate regulated in the sinoatrial node? Another piece to the puzzleI(f) and SR Ca(2+) release both contribute to pacemaker activity in canine sinoatrial node cellsA coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.A paradigm shift for the heart's pacemaker.The in vivo regulation of heart rate in the murine sinoatrial node by stimulatory and inhibitory heterotrimeric G proteins.A novel quantitative explanation for the autonomic modulation of cardiac pacemaker cell automaticity via a dynamic system of sarcolemmal and intracellular proteins.Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial nodeNonlinear and Stochastic Dynamics in the HeartCardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivationBK channels regulate sinoatrial node firing rate and cardiac pacing in vivoThe role of the calcium and the voltage clocks in sinoatrial node dysfunction.SHOX2 overexpression favors differentiation of embryonic stem cells into cardiac pacemaker cells, improving biological pacing ability.Catecholamine-independent heart rate increases require Ca2+/calmodulin-dependent protein kinase II.From two competing oscillators to one coupled-clock pacemaker cell systemCycle length restitution in sinoatrial node cells: a theory for understanding spontaneous action potential dynamics.Store-operated calcium entry and the localization of STIM1 and Orai1 proteins in isolated mouse sinoatrial node cells.Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1.Autonomic and endocrine control of cardiovascular functionThe genetic basis for inherited forms of sinoatrial dysfunction and atrioventricular node dysfunctionCa2+-activated adenylyl cyclase 1 introduces Ca2+-dependence to beta-adrenergic stimulation of HCN2 current.Ca(2+)-stimulated adenylyl cyclase AC1 generates efficient biological pacing as single gene therapy and in combination with HCN2
P2860
Q26746023-BA089AFD-303D-41C7-9683-1D645F12CFF1Q26747152-B49F9DFE-163A-44A9-A7A2-C41BDA4D9038Q26771350-92C2B509-EE5F-4715-A265-37DFB6A987CDQ26781422-D62CD68C-71AC-4009-A38C-15AC857EB9E2Q26827784-AD1E8BB6-2A34-400F-817F-718FE2321601Q26828018-B7BC8B02-F082-4152-9490-5C81CAA1BAEDQ26829681-D7CB6940-C085-4973-AF5E-3AA6F2427A5AQ26999230-A63DDAD0-6B3C-4B72-96C1-DF1480B782D2Q27008871-8C57EC8F-C649-41BF-B7AE-0E25E4C9CC47Q27023389-467BF892-75D0-4933-9BE5-25A968BCA890Q27330969-EA03A326-0109-448A-B19B-4E2FD3FC89EAQ28072418-837D3402-B882-497D-897C-97A239968B8AQ28080424-D493B4E1-E1C1-4262-B5BC-8A576F9FD2E8Q28085170-3E9A19E9-72E3-451B-861E-8AD0B37759CEQ28272583-76BF2C8F-FE55-4C8C-9F4E-88A7A59A65EFQ30498016-C60E1A8E-83A5-48BE-A68D-C06A4550BB91Q30499648-51B4B888-5F9E-4D3E-BED2-E1152419BCD4Q30579665-7CE620EE-D528-433C-A032-12635B7F7782Q33161429-0B5274E8-1188-4B91-8386-E7B964F5FB2FQ33349609-8291163C-06F6-4942-873B-0C0D8695F065Q33551644-627C29FF-738E-471B-A962-1C5D136AEF09Q33722486-0AACDFB4-12DF-4A9A-8406-FE244F55F298Q33760441-DCA0A93B-46C5-4426-989C-E57193F8A428Q33816888-E23DCF98-BC40-4E8C-8C05-283DB61C0CD5Q33917214-C9511FA2-DBAF-496D-A48D-A3A4F3A2FEE9Q34096457-26419101-DDB6-4F8A-AC43-B4966F051108Q34245774-8FB45D91-EB9F-4F51-9855-0E9A528F5CC4Q34392423-806BF5C4-7E29-4E39-BA3B-650FF6972669Q34439967-476D1C90-A134-47DE-B155-5659C8A1EDA8Q34635508-E36E3C7E-CFE1-4227-8F0C-09C9B89230ABQ34980766-45EEEA1D-D66E-418B-9A63-735C77258B2AQ35048166-AAE34B22-ABD3-4764-B3A7-4FE99D9ADB8DQ35081445-677F9243-6034-4399-91B5-23F2ABED014EQ35095636-3F6AA803-4538-4AAF-8EC6-1C2BC7766CA7Q35158231-7B060921-AEE2-409F-A071-DA0BB5A5E9AFQ35176492-EE596142-3104-466E-80D9-1372BBC68A95Q35501160-2D4CB611-E6D1-4EE8-B924-31C8A41ABE0DQ35800619-8600C595-7809-4A45-A586-46CB51B80D8DQ35947167-8EF4B149-045A-4283-BA81-F6788FD73A8FQ36160973-AA3E5047-388D-4164-B440-F2911FF2D0A2
P2860
What keeps us ticking: a funny current, a calcium clock, or both?
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
What keeps us ticking: a funny current, a calcium clock, or both?
@ast
What keeps us ticking: a funny current, a calcium clock, or both?
@en
type
label
What keeps us ticking: a funny current, a calcium clock, or both?
@ast
What keeps us ticking: a funny current, a calcium clock, or both?
@en
prefLabel
What keeps us ticking: a funny current, a calcium clock, or both?
@ast
What keeps us ticking: a funny current, a calcium clock, or both?
@en
P2860
P1476
What keeps us ticking: a funny current, a calcium clock, or both?
@en
P2093
Dario DiFrancesco
P2860
P304
P356
10.1016/J.YJMCC.2009.03.022
P577
2009-04-08T00:00:00Z