Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme. - Wikidata - awgldk - TriplyDB

Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

http://www.wikidata.org/entity/Q36016766

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Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease Neuroinflammation in Alzheimer's disease Oxidized cholesterol as the driving force behind the development of Alzheimer's disease Spreading of pathology in neurodegenerative diseases: a focus on human studies Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid BACE1 levels by APOE genotype in non-demented and Alzheimer's post-mortem brains Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brains Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer's Disease Neurological diseases as primary gliopathies: a reassessment of neurocentrism Protease inhibitors as potential disease-modifying therapeutics for Alzheimer's disease.Administration of NaHS Attenuates Footshock-Induced Pathologies and Emotional and Cognitive Dysfunction in Triple Transgenic Alzheimer's Mice.Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons The Alzheimer's disease beta-secretase enzyme, BACE1.BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer's disease Expression of familial Alzheimer disease presenilin 1 gene attenuates vesicle traffic and reduces peptide secretion in cultured astrocytes devoid of pathologic tissue environment.Astroglia in neurological diseases PATHOBIOLOGY OF NEURODEGENERATION: THE ROLE FOR ASTROGLIA.CCR5 deficiency accelerates lipopolysaccharide-induced astrogliosis, amyloid-beta deposit and impaired memory function.The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimer's Disease.Astrocyte-neuron interactions in neurological disorders.Cell biology, regulation and inhibition of beta-secretase (BACE-1).Placenta-derived mesenchymal stem cells improve memory dysfunction in an Aβ1-42-infused mouse model of Alzheimer's disease.Can BACE1 inhibition mitigate early axonal pathology in neurological diseases?Astrocytes in Alzheimer's disease.Oxidative stress and β-amyloid protein in Alzheimer's disease.Membrane trafficking pathways in Alzheimer's disease.Roles of AMP-activated protein kinase in Alzheimer's disease.Astrocyte signaling and neurodegeneration: new insights into CNS disorders.The neglected co-star in the dementia drama: the putative roles of astrocytes in the pathogeneses of major neurocognitive disorders.The Essential Role of Soluble Aβ Oligomers in Alzheimer's Disease.Involvement of inflammation in Alzheimer's disease pathogenesis and therapeutic potential of anti-inflammatory agents.Activation of 5-HT(2C) receptor promotes the expression of neprilysin in U251 human glioma cells.Astrocytes and synaptic plasticity in health and disease.Astrocyte dysfunction in Alzheimer disease.Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.KRICT-9 inhibits neuroinflammation, amyloidogenesis and memory loss in Alzheimer's disease models.Role of TGFβ signaling in the pathogenesis of Alzheimer's disease.Inhibition of cyclin-dependent kinase 5 affects early neuroinflammatory signalling in murine model of amyloid beta toxicity.The role of astrocytes in amyloid production and Alzheimer's disease.Upregulation of astrocytes protein phosphatase-2A stimulates astrocytes migration via inhibiting p38 MAPK in tg2576 mice.

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P2860

Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

http://www.wikidata.org/entity/Q36016766

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Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

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Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

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Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

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Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

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Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

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Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

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J.1471-4159.2004.02857.X

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Journal of Neurochemistry

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Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.

@en

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Christine Lange-Dohna

http://www.w3.org/2001/XMLSchema#string

J Regino Perez-Polo

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Steffen Rossner

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Ulrike Zeitschel

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P2860

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

Purification and cloning of amyloid precursor protein beta-secretase from human brain

Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties

The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology.

Maturation and pro-peptide cleavage of beta-secretase.

Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent.

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Alzheimer's disease