Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes
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Chronic intermittent psychological stress promotes macrophage reverse cholesterol transport by impairing bile acid absorption in mice.The anti-cholesterolaemic effect of a consortium of probiotics: An acute study in C57BL/6J mice.Epigenetic modulation of intestinal cholesterol transporter Niemann-Pick C1-like 1 (NPC1L1) gene expression by DNA methylation.Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins.Relative roles of ABCG5/ABCG8 in liver and intestine.Scap is required for sterol synthesis and crypt growth in intestinal mucosa.Glucagon receptor antagonism induces increased cholesterol absorption.The Interpretation of Cholesterol Balance Derived Synthesis Data and Surrogate Noncholesterol Plasma Markers for Cholesterol Synthesis under Lipid Lowering TherapiesCholesterol trials and mortality.Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.Insig proteins mediate feedback inhibition of cholesterol synthesis in the intestine.Ezetimibe markedly attenuates hepatic cholesterol accumulation and improves liver function in the lysosomal acid lipase-deficient mouse, a model for cholesteryl ester storage disease.Sustained and selective suppression of intestinal cholesterol synthesis by Ro 48-8071, an inhibitor of 2,3-oxidosqualene:lanosterol cyclase, in the BALB/c mouse.Investigational therapies for the treatment of atherosclerosis.Overactivation of intestinal Sterol Response Element Binding Protein 2 promotes diet-induced non-alcoholic steatohepatitis.Developmental and extrahepatic physiological functions of SREBP pathway genes in mice.Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine.Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase-deficient mice before and during treatment with ezetimibe.New Insights In Intestinal Sar1B GTPase Regulation and Role in Cholesterol Homeostasis.Overactivation of intestinal SREBP2 in mice increases serum cholesterol.Ezetimibe increases intestinal expression of the LDL receptor gene in dyslipidaemic men with insulin resistance.Effectiveness and safety of combinational therapy compared with intensified statin monotherapy in patients with coronary heart disease.Para-bile-osis Establishes a Role for Nonbiliary Macrophage to Feces Reverse Cholesterol Transport.
P2860
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P2860
Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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name
Blockade of cholesterol absorp ...... ostatic network in enterocytes
@ast
Blockade of cholesterol absorp ...... ostatic network in enterocytes
@en
type
label
Blockade of cholesterol absorp ...... ostatic network in enterocytes
@ast
Blockade of cholesterol absorp ...... ostatic network in enterocytes
@en
prefLabel
Blockade of cholesterol absorp ...... ostatic network in enterocytes
@ast
Blockade of cholesterol absorp ...... ostatic network in enterocytes
@en
P2093
P2860
P356
P1476
Blockade of cholesterol absorp ...... ostatic network in enterocytes
@en
P2093
Christina K Li
Guosheng Liang
Luke J Engelking
Matthew R McFarlane
P2860
P304
P356
10.1194/JLR.M027599
P577
2012-04-22T00:00:00Z