Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences.
about
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayXLS (c9orf142) is a new component of mammalian DNA double-stranded break repairHomologous recombination in DNA repair and DNA damage toleranceLymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombinationEssential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytesIn vivo veritas: using yeast to probe the biological functions of G-quadruplexesLack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining eventsModeling the study of DNA damage responses in miceDNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choiceImpact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaksNoncanonical views of homology-directed DNA repairThe response to and repair of RAG-mediated DNA double-strand breaksRole of non-homologous end joining in V(D)J recombinationA chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouseRepair at single targeted DNA double-strand breaks in pluripotent and differentiated human cellsPTIP promotes chromatin changes critical for immunoglobulin class switch recombinationThe transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cellsDouble strand break repair functions of histone H2AXRole of mammalian Mre11 in classical and alternative nonhomologous end joiningDual functions of Nbs1 in the repair of DNA breaks and proliferation ensure proper V(D)J recombination and T-cell development.Elucidating the domain architecture and functions of non-core RAG1: the capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid bindingMechanisms of chromosomal rearrangement in the human genomeDevelopment and analysis of a germline BAC resource for the sea lamprey, a vertebrate that undergoes substantial chromatin diminutionAID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndromeDownstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions.Is homologous recombination really an error-free process?Elucidation of IgH intronic enhancer functions via germ-line deletionHIV-1 infection in Zambian children impairs the development and avidity maturation of measles virus-specific immunoglobulin G after vaccination and infection.H2AX post-translational modifications in the ionizing radiation response and homologous recombination.Modeling DNA polymerase μ motions: subtle transitions before chemistry.Roles for histone H3K4 methyltransferase activities during immunoglobulin class-switch recombinationMechanisms of double-strand break repair in somatic mammalian cells.Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell.The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination.Tying the loose ends together in DNA double strand break repair with 53BP1.The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombinationActivation of 12/23-RSS-dependent RAG cleavage by hSWI/SNF complex in the absence of transcription.Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
P2860
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P2860
Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Mechanism and control of V(D)J ...... similarities and differences.
@ast
Mechanism and control of V(D)J ...... similarities and differences.
@en
type
label
Mechanism and control of V(D)J ...... similarities and differences.
@ast
Mechanism and control of V(D)J ...... similarities and differences.
@en
prefLabel
Mechanism and control of V(D)J ...... similarities and differences.
@ast
Mechanism and control of V(D)J ...... similarities and differences.
@en
P2093
P1476
Mechanism and control of V(D)J ...... similarities and differences.
@en
P2093
Craig H Bassing
Darryll D Dudley
Frederick W Alt
Jayanta Chaudhuri
P304
P356
10.1016/S0065-2776(04)86002-4
P577
2005-01-01T00:00:00Z