Regulation of a nuclear export signal by an adjacent inhibitory sequence: the effector domain of the influenza virus NS1 protein
about
Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replicationHerpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathwaysIntegrating historical, clinical and molecular genetic data in order to explain the origin and virulence of the 1918 Spanish influenza virusA masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesisSequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genesNucleocytoplasmic shuttling of influenza A virus proteinsPDlim2 Selectively Interacts with the PDZ Binding Motif of Highly Pathogenic Avian H5N1 Influenza A Virus NS1Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor.The Influenza NS1 Protein: What Do We Know in Equine Influenza Virus Pathogenesis?Functions of the influenza A virus NS1 protein in antiviral defenseNuclear Translocation of Crk Adaptor Proteins by the Influenza A Virus NS1 Protein.The origin and virulence of the 1918 "Spanish" influenza virus.Persistent host markers in pandemic and H5N1 influenza virusesComplete-proteome mapping of human influenza A adaptive mutations: implications for human transmissibility of zoonotic strains.Genetic analysis of influenza virus NS1 gene: a temperature-sensitive mutant shows defective formation of virus particles.Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression.Identification of an export control sequence and a requirement for the KH domains in ICP27 from herpes simplex virus type 1Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 proteinA nuclear localization of the infectious haematopoietic necrosis virus NV protein is necessary for optimal viral growth.Comparative analysis of seven viral nuclear export signals (NESs) reveals the crucial role of nuclear export mediated by the third NES consensus sequence of nucleoprotein (NP) in influenza A virus replication.Intracellular distribution of NS1 correlates with the infectivity and interferon antagonism of an avian influenza virus (H7N1).Signals that dictate nuclear, nucleolar, and cytoplasmic shuttling of the gamma(1)34.5 protein of herpes simplex virus type 1Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarinThe first identified nucleocytoplasmic shuttling herpesviral capsid protein: herpes simplex virus type 1 VP19C.The NS1 protein of influenza A virus interacts with cellular processing bodies and stress granules through RNA-associated protein 55 (RAP55) during virus infectionExploring naphthyl-carbohydrazides as inhibitors of influenza A viruses.Identification of adaptive mutations in the influenza A virus non-structural 1 gene that increase cytoplasmic localization and differentially regulate host gene expressionA Closer Look at the NS1 of Influenza Virus.Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome.Influenza virus targets the mRNA export machinery and the nuclear pore complex.The RNA binding domain of influenza A virus NS1 protein affects secretion of tumor necrosis factor alpha, interleukin-6, and interferon in primary murine tracheal epithelial cellsContribution of NS1 effector domain dimerization to influenza A virus replication and virulence.Adaptive mutation in influenza A virus non-structural gene is linked to host switching and induces a novel protein by alternative splicingSUMOylation affects the interferon blocking activity of the influenza A nonstructural protein NS1 without affecting its stability or cellular localization.Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30Defective RNA replication and late gene expression in temperature-sensitive influenza viruses expressing deleted forms of the NS1 proteinTargeting cell division cycle 25 homolog B to regulate influenza virus replication.hnRNP A2/B1 interacts with influenza A viral protein NS1 and inhibits virus replication potentially through suppressing NS1 RNA/protein levels and NS1 mRNA nuclear exportEmergence of a highly pathogenic avian influenza virus from a low-pathogenic progenitor.An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells.
P2860
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P2860
Regulation of a nuclear export signal by an adjacent inhibitory sequence: the effector domain of the influenza virus NS1 protein
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Regulation of a nuclear export ...... he influenza virus NS1 protein
@ast
Regulation of a nuclear export ...... he influenza virus NS1 protein
@en
type
label
Regulation of a nuclear export ...... he influenza virus NS1 protein
@ast
Regulation of a nuclear export ...... he influenza virus NS1 protein
@en
prefLabel
Regulation of a nuclear export ...... he influenza virus NS1 protein
@ast
Regulation of a nuclear export ...... he influenza virus NS1 protein
@en
P2093
P2860
P356
P1476
Regulation of a nuclear export ...... he influenza virus NS1 protein
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.9.4864
P407
P577
1998-04-01T00:00:00Z