A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis - Wikidata - awgldk - TriplyDB

A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis

A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis

http://www.wikidata.org/entity/Q36105991

about

Pulmonary Tuberculosis Diagnosis: Where We Are?The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosis Tuberculosis drug discovery in the post-post-genomic era Identification of a small molecule with activity against drug-resistant and persistent tuberculosis New target prediction and visualization tools incorporating open source molecular fingerprints for TB Mobile 2.0 First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB Enhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian models TB Mobile: a mobile app for anti-tuberculosis molecules with known targets Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.Metabolic Perspectives on Persistence Fusing dual-event data sets for Mycobacterium tuberculosis machine learning models and their evaluation.Characterization of the type 2 NADH:menaquinone oxidoreductases from Staphylococcus aureus and the bactericidal action of phenothiazines Isolation and Characterization of a Hybrid Respiratory Supercomplex Consisting of Mycobacterium tuberculosis Cytochrome bcc and Mycobacterium smegmatis Cytochrome aa3.Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis.Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis.High-throughput screening of small molecule ligands targeted to live bacteria surface.Bayesian models leveraging bioactivity and cytotoxicity information for drug discovery.Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation model Combining computational methods for hit to lead optimization in Mycobacterium tuberculosis drug discovery.Single-cell tracking reveals antibiotic-induced changes in mycobacterial energy metabolism.Bayesian models for screening and TB Mobile for target inference with Mycobacterium tuberculosis.Putting Tuberculosis (TB) To Rest: Transformation of the Sleep Aid, Ambien, and "Anagrams" Generated Potent Antituberculosis Agents.The tuberculosis drug discovery and development pipeline and emerging drug targets.Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents.Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence.SAR and identification of 2-(quinolin-4-yloxy)acetamides as Mycobacterium tuberculosis cytochrome bc1 inhibitors Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor.Advancement of Imidazo[1,2-a]pyridines with Improved Pharmacokinetics and Nanomolar Activity Against Mycobacterium tuberculosis.Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.Imidazo[1,2-a]Pyridine-3-Carboxamides Are Active Antimicrobial Agents against Mycobacterium avium Infection In Vivo Advances in Drug Discovery and Development for Pediatric Tuberculosis.Elucidating population-wide mycobacterial replication dynamics at the single-cell level Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival of Mycobacterium tuberculosis on fatty acids Resistance in tuberculosis: what do we know and where can we go?Tuberculosis drug discovery and emerging targets.The future for early-stage tuberculosis drug discovery Unconventional screening approaches for antibiotic discovery.Oxidative Phosphorylation as a Target Space for Tuberculosis: Success, Caution, and Future Directions.System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis.

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P2860

A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis

http://www.wikidata.org/entity/Q36105991

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

A high-throughput screen to id ...... ing Mycobacterium tuberculosis

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A high-throughput screen to id ...... ing Mycobacterium tuberculosis

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type

label

A high-throughput screen to id ...... ing Mycobacterium tuberculosis

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A high-throughput screen to id ...... ing Mycobacterium tuberculosis

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prefLabel

A high-throughput screen to id ...... ing Mycobacterium tuberculosis

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A high-throughput screen to id ...... ing Mycobacterium tuberculosis

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ACS Chemical Biology

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A high-throughput screen to id ...... ing Mycobacterium tuberculosis

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Arnab Chatterjee

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Bee Huat Tan

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Boon Heng Lee

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David Beer

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Frantisek Supek

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Helena I Boshoff

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Jason Chyba

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Jeyaraj Duraiswamy

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Joann Tay

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Kelli Kuhen

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P2860

The complete genome sequence of Mycobacterium bovis

Effects of pyrazinamide on fatty acid synthesis by whole mycobacterial cells and purified fatty acid synthase I.

The mechanism of action of PA-824: Novel insights from transcriptional profiling

The enduring hypoxic response of Mycobacterium tuberculosis

Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus

Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project

The diarylquinoline TMC207 for multidrug-resistant tuberculosis

An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence

Two sensor kinases contribute to the hypoxic response of Mycobacterium tuberculosis

Diarylquinolines target subunit c of mycobacterial ATP synthase

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1190-1197

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scholarly article

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10.1021/CB2004884

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7

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7

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Clifton E Barry

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2012-04-25T00:00:00Z

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224034449

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22500615

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P921

Mycobacterium tuberculosis

P932

3401038

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