Messenger RNA deadenylylation precedes decapping in mammalian cells.
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The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activityTranslational repression precedes and is required for ZAP-mediated mRNA decayThe scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatasesDegradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes.Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.A pathway for the biogenesis of trans-acting siRNAs in ArabidopsisAU-rich elements and associated factors: are there unifying principles?The hDcp2 protein is a mammalian mRNA decapping enzymeThe GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodiesHuman Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structuresA novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elementsAn mRNA stability complex functions with poly(A)-binding protein to stabilize mRNA in vitroIdentification of a chitin-induced small RNA that regulates translation of the tfoX gene, encoding a positive regulator of natural competence in Vibrio choleraeCap-dependent deadenylation of mRNAePAT: a simple method to tag adenylated RNA to measure poly(A)-tail length and other 3' RACE applicationsHuman let-7 stem-loop precursors harbor features of RNase III cleavage productsInteraction between a poly(A)-specific ribonuclease and the 5' cap influences mRNA deadenylation rates in vitroCytoplasmic foci are sites of mRNA decay in human cellsDcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathwaySerum-deprivation stimulates cap-binding by PARN at the expense of eIF4E, consistent with the observed decrease in mRNA stabilityBiogenesis, turnover, and mode of action of plant microRNAsRegulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex.Two related proteins, Edc1p and Edc2p, stimulate mRNA decapping in Saccharomyces cerevisiaeThe yeast POP2 gene encodes a nuclease involved in mRNA deadenylation.Regulation of ARE transcript 3' end processing by the yeast Cth2 mRNA decay factorCcr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiaeA 54-kDa fragment of the Poly(A)-specific ribonuclease is an oligomeric, processive, and cap-interacting Poly(A)-specific 3' exonucleaseThe mRNA cap structure stimulates rate of poly(A) removal and amplifies processivity of degradationAnalysis of the function, expression, and subcellular distribution of human tristetraprolinRegulation of serum amyloid A protein expression during the acute-phase responseMessenger RNA turnover in eukaryotes: pathways and enzymesA cis-acting element known to block 3' mRNA degradation enhances expression of polyA-minus mRNA in wild-type yeast cells and phenocopies a ski mutantRegulation of heme oxygenase-1 mRNA deadenylation and turnover in NIH3T3 cells by nitrosative or alkylation stressAn integrated in silico approach to design specific inhibitors targeting human poly(a)-specific ribonucleaseWidespread transcription at neuronal activity-regulated enhancersComponents of the Arabidopsis mRNA decapping complex are required for early seedling development.Uncoupling ribosome biogenesis regulation from RNA polymerase I activity during herpes simplex virus type 1 infectionControl of messenger RNA fate by RNA-binding proteins: an emphasis on mammalian spermatogenesis
P2860
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P2860
Messenger RNA deadenylylation precedes decapping in mammalian cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Messenger RNA deadenylylation precedes decapping in mammalian cells.
@ast
Messenger RNA deadenylylation precedes decapping in mammalian cells.
@en
type
label
Messenger RNA deadenylylation precedes decapping in mammalian cells.
@ast
Messenger RNA deadenylylation precedes decapping in mammalian cells.
@en
prefLabel
Messenger RNA deadenylylation precedes decapping in mammalian cells.
@ast
Messenger RNA deadenylylation precedes decapping in mammalian cells.
@en
P2093
P2860
P356
P1476
Messenger RNA deadenylylation precedes decapping in mammalian cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.11.5628
P407
P577
1997-05-01T00:00:00Z