OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance
about
DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic TargetsTau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.FOXM1 is a therapeutic target for high-risk multiple myeloma.OTUB1 promotes tumor invasion and predicts a poor prognosis in gastric adenocarcinoma.RNF168 cooperates with RNF8 to mediate FOXM1 ubiquitination and degradation in breast cancer epirubicin treatmentOTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer.miR-542-3p inhibits colorectal cancer cell proliferation, migration and invasion by targeting OTUB1.p62/SQSTM1 enhances breast cancer stem-like properties by stabilizing MYC mRNA.FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop.Expression of OTUB1 in hepatocellular carcinoma and its effects on HCC cell migration and invasion.Forkhead box K2 modulates epirubicin and paclitaxel sensitivity through FOXO3a in breast cancer.Silencing of OTUB1 inhibits migration of human glioma cells in vitro.The role of deubiquitinases in breast cancer.The importance of regulatory ubiquitination in cancer and metastasis.Roles of FoxM1 in cell regulation and breast cancer targeting therapy.Suppressor of fused (Sufu) promotes epithelial-mesenchymal transition (EMT) in cervical squamous cell carcinoma.FoxM1 is a promising candidate target in the treatment of breast cancer.Otubain 1: a non-canonical deubiquitinase with an emerging role in cancerRegulation of the master regulator FOXM1 in cancer
P2860
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P2860
OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
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name
OTUB1 inhibits the ubiquitinat ...... ncer and epirubicin resistance
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OTUB1 inhibits the ubiquitinat ...... ncer and epirubicin resistance
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type
label
OTUB1 inhibits the ubiquitinat ...... ncer and epirubicin resistance
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OTUB1 inhibits the ubiquitinat ...... ncer and epirubicin resistance
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prefLabel
OTUB1 inhibits the ubiquitinat ...... ncer and epirubicin resistance
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OTUB1 inhibits the ubiquitinat ...... ncer and epirubicin resistance
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P2093
P2860
P50
P356
P1433
P1476
OTUB1 inhibits the ubiquitinat ...... ncer and epirubicin resistance
@en
P2093
J W-H Tsang
M Kongsema
P Khongkow
U Karunarathna
P2860
P2888
P304
P356
10.1038/ONC.2015.208
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P577
2015-07-06T00:00:00Z